MS103 Complex I subunit GRIM-19
monoclonal antibody


$295.00 (100 g)

Please contact us for volume discounts.
This product can also be ordered as part of a sample pack.



Brief Description & Uses

100 g of monoclonal antibody reactive against the 19 kDa Complex I (NADH dehydrogenase) subunit GRIM-19. MS103 also labels GRIM-19 in immunocytochemical applications. Isolated mitochondria are available from several species for use as control samples. To see the complete list of control samples available from MitoSciences, click here.

GRIM-19 (Gene associated with Retinoid IFN induced Mortality) was first described as an apoptotic factor located in the cytosol and nucleus of cells undergoing programmed cell death. Recently this same protein was shown to be a subunit of Complex I in bovine and human mitochondria.

The anti GRIM-19 mAb reacts specifically in Western blots and immunocytochemistry, and shows cross reactivity with human, bovine, mouse and rat tissues. This mAb can be used to evaluate the interaction of GRIM-19 with Complex I in vivo or after immunocapture as a result of various cell treatments and may also be useful in other kinds of studies of apoptosis.


Specifications

Product: Complex I subunit GRIM-19
monoclonal antibody
Catalog #: MS103
Lot #:
Clone ID: 6E1BH7
Host Species and Isotype: Mouse IgG2b, κ
Immunogen: Full-length recombinant human GRIM-19
Concentration: 1 mg/ml in Dulbecco’s Phosphate-Buffered Saline (PBS) with 0.02% azide as a preservative.
Purity: Near homogeneity as judged by SDS-PAGE. The antibodies were produced in vitro using hybridomas grown in serum-free medium, and then purified by biochemical fractionation.
Suggested Working Concentration: 1 g/ml for Western blotting, 1 g/ml for Immunocytochemistry
Applications: Western blotting, Immunocytochemistry
(heat-induced antigen-retrieval improves signal)
Antigen Species Cross-Reactivity: human, bovine, mouse and rat
Storage: 4C
Country of Origin: USA



Product References




References for Complex I subunit GRIM-19




Images

GRIM-19 Western Blotting Image


GRIM-19 Immunocytochemistry Image


Downloadable Information
MS101 Specifications Western Blotting Protocol Immunocytochemistry Protocol


Additional Information
Product Images
Product References
Protein References


Related Products
Western Blotting Controls

Secondary Antibodies

MS851 Isolation Kit for Rodent Tissue
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