Publications referencing MitoSciences Products - MitoNews July 2014

Intermittent and continuous high-intensity exercise induce similar acute but different chronic muscle training adaptations.
Cochran AJ, Percival ME, Tricarico S, Little JP, Cermak N, Gillen JB, Tarnopolsky MA, Gibala MJ.


Safety and tolerability of carbamylated erythropoietin in Friedreich's ataxia.
Boesch S, Nachbauer W, Mariotti C, Sacca F, Filla A, Klockgether T, Klopstock T, Sch??ls L, Jacobi H, B??chner B, Vom Hagen JM, Nanetti L, Manicom K.


High-fat diet-induced mitochondrial biogenesis is regulated by mitochondrial-derived reactive oxygen species activation of CaMKII.
Jain SS, Paglialunga S, Vigna C, Ludzki A, Herbst EA, Lally JS, Schrauwen P, Hoeks J, Tupling AR, Bonen A, Holloway GP.


Modulation of cardiac mitochondrial permeability transition and apoptotic signaling by endurance training and intermittent hypobaric hypoxia.
Magalh??es J, Gon??alves IO, Lumini-Oliveira J, Marques-Aleixo I, Passos E, Rocha-Rodrigues S, Machado NG, Moreira AC, Rizo D, Viscor G, Oliveira PJ, Torrella JR, Ascens??o A.


Generation and characterisation of Friedreich ataxia YG8R mouse fibroblast and neural stem cell models.
Sandi C, Sandi M, Jassal H, Ezzatizadeh V, Anjomani-Virmouni S, Al-Mahdawi S, Pook MA.


Overexpression of Mitofilin in the Mouse Heart Promotes Cardiac Hypertrophy in Response to Hypertrophic Stimuli.
Zhang Y, Xu J, Luo YX, An XZ, Zhang R, Liu G, Li H, Chen HZ, Liu DP.


Targeting unique metabolic properties of breast tumor initiating cells.
Feng W, Gentles A, Nair RV, Huang M, Lin Y, Lee CY, Cai S, Scheeren FA, Kuo AH, Diehn M.


Mitochondrial targeting of cytochrome P450 (CYP) 1B1 and its role in polycyclic aromatic hydrocarbon-induced mitochondrial dysfunction.
Bansal S, Leu AN, Gonzalez FJ, Guengerich FP, Chowdhury AR, Anandatheerthavarada HK, Avadhani NG.


Resveratrol restores sirtuin 1 (SIRT1) activity and pyruvate dehydrogenase kinase 1 (PDK1) expression after hemorrhagic injury in a rat model.
Jian B, Yang S, Chaudry IH, Raju R.


Novel effects of rosiglitazone on SMAD2 and SMAD3 signaling in white adipose tissue of diabetic rats.
Beaudoin MS, Snook LA, Arkell AM, Stefanson A, Wan Z, Simpson JA, Holloway GP, Wright DC.


Epicatechin stimulates mitochondrial activity and selectively sensitizes cancer cells to radiation.
Elbaz HA, Lee I, Antwih DA, Liu J, H??ttemann M, Zielske SP.


Mitochondrial efficiency is increased in axenically cultured Caenorhabditis elegans.
Castelein N, Muschol M, Dhondt I, Cai H, De Vos WH, Dencher NA, Braeckman BP.


Altered lipid composition in cortical lipid rafts occurs at early stages of sporadic Alzheimer's disease and facilitates APP/BACE1 interactions.
Fabelo N, Mart??n V, Mar??n R, Moreno D, Ferrer I, D??az M.


Mitochondrial proteome remodeling in ischemic heart failure.
Liu T, Chen L, Kim E, Tran D, Phinney BS, Knowlton AA.


Actein isolated from black cohosh promotes the function of osteoblastic MC3T3-E1 cells.
Lee YS, Choi EM.


Decrease of reactive oxygen species-related biomarkers in the tissue-mimic 3D spheroid culture of human lung cells exposed to zinc oxide nanoparticles.
Kim E, Jeon WB, Kim S, Lee SK.


Epigenetic upregulation of endogenous VEGF-A reduces myocardial infarct size in mice.
Turunen MP, Husso T, Musthafa H, Laidinen S, Dragneva G, Laham-Karam N, Honkanen S, Paakinaho A, Laakkonen JP, Gao E, Vihinen-Ranta M, Liimatainen T, Yl??-Herttuala S.


Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations.
Gammage PA, Rorbach J, Vincent AI, Rebar EJ, Minczuk M.


NSUN4 is a dual function mitochondrial protein required for both methylation of 12S rRNA and coordination of mitoribosomal assembly.
Metodiev MD, Sp??hr H, Loguercio Polosa P, Meharg C, Becker C, Altmueller J, Habermann B, Larsson NG, Ruzzenente B.


IL-15 maintains T-cell survival via S-nitrosylation-mediated inhibition of caspase-3.
Saligrama PT, Fortner KA, Secinaro MA, Collins CC, Russell JQ, Budd RC.


Blockade of BFA-mediated apoptosis in macrophages by the HIV-1 Nef protein.
Abbas W, Khan KA, Kumar A, Tripathy MK, Dichamp I, Keita M, Mahlknecht U, Rohr O, Herbein G.


TLR-driven early glycolytic reprogramming via the kinases TBK1-IKK?? supports the anabolic demands of dendritic cell activation.
Everts B, Amiel E, Huang SC, Smith AM, Chang CH, Lam WY, Redmann V, Freitas TC, Blagih J, van der Windt GJ, Artyomov MN, Jones RG, Pearce EL, Pearce EJ.


Induced pluripotent stem cells with a mitochondrial DNA deletion.
Cherry AB, Gagne KE, McLoughlin EM, Baccei A, Gorman B, Hartung O, Miller JD, Zhang J, Zon RL, Ince TA, Neufeld EJ, Lerou PH, Fleming MD, Daley GQ, Agarwal S.


Hepatocytes determine the hypoxic microenvironment and radiosensitivity of colorectal cancer cells through production of nitric oxide that targets mitochondrial respiration.
Jiang H, Verovski VN, Leonard W, Law KL, Vermeersch M, Storme G, Van den Berge D, Gevaert T, Sermeus A, De Ridder M.


PGC-1?? mediates adaptive chemoresistance associated with mitochondrial DNA mutations.
Yao Z, Jones AW, Fassone E, Sweeney MG, Lebiedzinska M, Suski JM, Wieckowski MR, Tajeddine N, Hargreaves IP, Yasukawa T, Tufo G, Brenner C, Kroemer G, Rahman S, Szabadkai G.


The C8ORF38 homologue Sicily is a cytosolic chaperone for a mitochondrial complex I subunit.
Zhang K, Li Z, Jaiswal M, Bayat V, Xiong B, Sandoval H, Charng WL, David G, Haueter C, Yamamoto S, Graham BH, Bellen HJ.


Endogenous ovarian hormones affect mitochondrial efficiency in cerebral endothelium via distinct regulation of PGC-1 isoforms.
Kemper MF, Zhao Y, Duckles SP, Krause DN.


Clinical use of frataxin measurement in a patient with a novel deletion in the FXN gene.
Sacc?? F, Marsili A, Puorro G, Antenora A, Pane C, Tessa A, Scoppettuolo P, Nesti C, Brescia Morra V, De Michele G, Santorelli FM, Filla A.


Phenylbutyrate therapy for pyruvate dehydrogenase complex deficiency and lactic acidosis.
Ferriero R, Manco G, Lamantea E, Nusco E, Ferrante MI, Sordino P, Stacpoole PW, Lee B, Zeviani M, Brunetti-Pierri N.


Multiple steps of HLA-G in ovarian carcinoma metastasis: alter NK cytotoxicity and induce matrix metalloproteinase-15 (MMP-15) expression.
Lin A, Xu HH, Xu DP, Zhang X, Wang Q, Yan WH.


Drosophila ref(2)P is required for the parkin-mediated suppression of mitochondrial dysfunction in pink1 mutants.
de Castro IP, Costa AC, Celardo I, Tufi R, Dinsdale D, Loh SH, Martins LM.


LYRM7/MZM1L is a UQCRFS1 chaperone involved in the last steps of mitochondrial Complex III assembly in human cells.
S??nchez E, Lobo T, Fox JL, Zeviani M, Winge DR, Fern??ndez-Vizarra E.


The oxidative stress in breast tumors of postmenopausal women is ER??/ER?? ratio dependent.
Sastre-Serra J, Nadal-Serrano M, Pons DG, Valle A, Garau I, Garc??a-Bonaf?? M, Oliver J, Roca P.


Mitochondrial and sarcoplasmic reticulum abnormalities in cancer cachexia: altered energetic efficiency?
Fontes-Oliveira CC, Busquets S, Toledo M, Penna F, Paz Aylwin M, Sirisi S, Silva AP, Orp?? M, Garc??a A, Sette A, In??s Genovese M, Olivan M, L??pez-Soriano FJ, Argil??s JM.


Expression and subcellular distribution of UNC119a, a protein partner of transducin ?? subunit in rod photoreceptors.
Sinha S, Majumder A, Belcastro M, Sokolov M, Artemyev NO.


Obesity affects mitochondrial citrate synthase in human omental adipose tissue.
Christe M, Hirzel E, Lindinger A, Kern B, von Fl??e M, Peterli R, Peters T, Eberle AN, Lindinger PW.


A high leucine diet mitigates cardiac injury and improves survival after acute myocardial infarction.
Witham WG, Yester KA, McGaffin KR.


REXO2 is an oligoribonuclease active in human mitochondria.
Bruni F, Gramegna P, Oliveira JM, Lightowlers RN, Chrzanowska-Lightowlers ZM.


A novel cinnamate derivative attenuates asthma features and reduces bronchial epithelial injury in mouse model.
Kumar S, Mabalirajan U, Rehman R, Singh BK, Parmar VS, Prasad AK, Biswal S, Ghosh B.


Primary fibroblasts of NDUFS4(-/-) mice display increased ROS levels and aberrant mitochondrial morphology.
Valsecchi F, Grefte S, Roestenberg P, Joosten-Wagenaars J, Smeitink JA, Willems PH, Koopman WJ.


Regulation of mitochondrial F(o)F(1)ATPase activity by Sirt3-catalyzed deacetylation and its deficiency in human cells harboring 4977bp deletion of mitochondrial DNA.
Wu YT, Lee HC, Liao CC, Wei YH.


B-cell translocation gene 2: expression in the rat ovary and potential association with adenine nucleotide translocase 2 in mitochondria.
Park JI, Kim SG, Baek MW, Park TJ, Lim IK, Seo YW, Chun SY.


Activating oxidative phosphorylation by a pyruvate dehydrogenase kinase inhibitor overcomes sorafenib resistance of hepatocellular carcinoma.
Shen YC, Ou DL, Hsu C, Lin KL, Chang CY, Lin CY, Liu SH, Cheng AL.


Mitochondrial citrate synthase crystals: novel finding in Sengers syndrome caused by acylglycerol kinase (AGK) mutations.
Siriwardena K, Mackay N, Levandovskiy V, Blaser S, Raiman J, Kantor PF, Ackerley C, Robinson BH, Schulze A, Cameron JM.


Mitigation of radiation injury by selective stimulation of the LPA(2) receptor.
Kiss GN, Lee SC, Fells JI, Liu J, Valentine WJ, Fujiwara Y, Thompson KE, Yates CR, S??megi B, Tigyi G.


Creating a tumor-resistant microenvironment: cell-mediated delivery of TNF?? completely prevents breast cancer tumor formation in vivo.
Al-Zoubi M, Salem AF, Martinez-Outschoorn UE, Whitaker-Menezes D, Lamb R, Hulit J, Howell A, Gandara R, Sartini M, Arafat H, Bevilacqua G, Sotgia F, Lisanti MP.


High-intensity exercise training induces morphological and biochemical changes in skeletal muscles.
Toti L, Bartalucci A, Ferrucci M, Fulceri F, Lazzeri G, Lenzi P, Soldani P, Gobbi P, La Torre A, Gesi M.


Cigarette smoke metabolically promotes cancer, via autophagy and premature aging in the host stromal microenvironment.
Salem AF, Al-Zoubi MS, Whitaker-Menezes D, Martinez-Outschoorn UE, Lamb R, Hulit J, Howell A, Gandara R, Sartini M, Galbiati F, Bevilacqua G, Sotgia F, Lisanti MP.


Optic atrophy 1 mediates mitochondria remodeling and dopaminergic neurodegeneration linked to complex I deficiency.
Ramonet D, Perier C, Recasens A, Dehay B, Bov?? J, Costa V, Scorrano L, Vila M.


Mutations in the lipoyltransferase LIPT1 gene cause a fatal disease associated with a specific lipoylation defect of the 2-ketoacid dehydrogenase complexes.
Tort F, Ferrer-Cort??s X, Thi?? M, Navarro-Sastre A, Matalonga L, Quintana E, Bujan N, Arias A, Garc??a-Villoria J, Acquaviva C, Vianey-Saban C, Artuch R, Garc??a-Cazorla ??, Briones P, Ribes A.


Adaptative capacity of mitochondrial biogenesis and of mitochondrial dynamics in response to pathogenic respiratory chain dysfunction.
Benard G, Trian T, Bellance N, Berger P, Lavie J, Espil-Taris C, Rocher C, Eimer-Bouillot S, Goizet C, Nouette-Gaulain K, Letellier T, Lacombe D, Rossignol R.


Mitochondrial respiratory supercomplex association limits production of reactive oxygen species from complex I.
Maranzana E, Barbero G, Falasca AI, Lenaz G, Genova ML.


Disrupted ATP synthase activity and mitochondrial hyperpolarisation-dependent oxidative stress is associated with p66Shc phosphorylation in fibroblasts of NARP patients.
Lebiedzinska M, Karkucinska-Wieckowska A, Wojtala A, Suski JM, Szabadkai G, Wilczynski G, Wlodarczyk J, Diogo CV, Oliveira PJ, Tauber J, Je??ek P, Pronicki M, Duszynski J, Pinton P, Wieckowski MR.


Increased mitochondrial activity in BMP7-treated brown adipocytes, due to increased CPT1- and CD36-mediated fatty acid uptake.
Townsend KL, An D, Lynes MD, Huang TL, Zhang H, Goodyear LJ, Tseng YH.


Mitochondrial dysfunction in the skeletal muscle of a mouse model of Rett syndrome (RTT): implications for the disease phenotype.
Gold WA, Williamson SL, Kaur S, Hargreaves IP, Land JM, Pelka GJ, Tam PP, Christodoulou J.


Succinate dehydrogenase deficiency is rare in pituitary adenomas.
Gill AJ, Toon CW, Clarkson A, Sioson L, Chou A, Winship I, Robinson BG, Benn DE, Clifton-Bligh RJ, Dwight T.


Regulation of O2 consumption by the PI3K and mTOR pathways contributes to tumor hypoxia.
Kelly CJ, Hussien K, Fokas E, Kannan P, Shipley RJ, Ashton TM, Stratford M, Pearson N, Muschel RJ.


Distinct palmitoylation events at the amino-terminal conserved cysteines of Env7 direct its stability, localization, and vacuolar fusion regulation in S. cerevisiae.
Manandhar SP, Calle EN, Gharakhanian E.


A Novel SUCLA2 Mutation in a Portuguese Child Associated With Mild' Methylmalonic Aciduria.'
Nogueira C, Meschini MC, Nesti C, Garcia P, Diogo L, Valongo C, Costa R, Videira A, Vilarinho L, Santorelli FM.


A comprehensive approach to determining BER capacities and their change with aging in Drosophila melanogaster mitochondria by oligonucleotide microarray.
Garreau-Balandier I, Lefebvre M, Jacquard S, Caillat S, Cruz-Rodriguez L, Ishak L, Agier V, Morel F, Lachaume P, Dubessay P, Sauvaigo S, Alziari S, Vernet P.


Effects of levosimendan on mitochondrial function in patients with??septic shock: A randomized trial.
Torraco A, Carrozzo R, Piemonte F, Pastore A, Tozzi G, Verrigni D, Assenza M, Orecchioni A, D'Egidio A, Marraffa E, Landoni G, Bertini E, Morelli A.


Rosamines targeting the cancer oxidative phosphorylation pathway.
Lim SH, Wu L, Kiew LV, Chung LY, Burgess K, Lee HB.


Sexual Dimorphism in the Alterations of Cardiac Muscle Mitochondrial Bioenergetics Associated to the Ageing Process.
Colom B, Oliver J, Garcia-Palmer FJ.


Platelet bioenergetic screen in sickle cell patients reveals mitochondrial complex V inhibition, which contributes to platelet activation.
Cardenes N, Corey C, Geary L, Jain S, Zharikov S, Barge S, Novelli EM, Shiva S.


Investigating Mitochondrial Metabolism in Contracting HL-1 Cardiomyocytes Following Hypoxia and Pharmacological HIF Activation Identifies HIF-Dependent and Independent Mechanisms of Regulation.
Ambrose LJ, Abd-Jamil AH, Gomes RS, Carter EE, Carr CA, Clarke K, Heather LC.


Modulating effect of SIRT1 activation induced by resveratrol on Foxo1-associated apoptotic signalling in senescent heart.
Sin TK, Yu AP, Yung BY, Yip SP, Chan LW, Wong CS, Ying M, Rudd JA, Siu PM.


TNFR1/phox interaction and TNFR1 mitochondrial translocation Thwart silica-induced pulmonary fibrosis.
Fazzi F, Njah J, Di Giuseppe M, Winnica DE, Go K, Sala E, St Croix CM, Watkins SC, Tyurin VA, Phinney DG, Fattman CL, Leikauf GD, Kagan VE, Ortiz LA.


Altered lipid composition in cortical lipid rafts occurs at early stages of sporadic Alzheimer's disease and facilitates APP/BACE1 interactions.
Fabelo N, Mart??n V, Mar??n R, Moreno D, Ferrer I, D??az M.


B7-H4 downregulation induces mitochondrial dysfunction and enhances doxorubicin sensitivity via the cAMP/CREB/PGC1-?? signaling pathway in HeLa cells.
Kim HK, Song IS, Lee SY, Jeong SH, Lee SR, Heo HJ, Thu VT, Kim N, Ko KS, Rhee BD, Jeong DH, Kim YN, Han J.


A mouse model of mitochondrial complex III dysfunction induced by myxothiazol.
Davoudi M, Kallij??rvi J, Marjavaara S, Kotarsky H, Hansson E, Lev??en P, Fellman V.


Impairments in mitochondrial palmitoyl-CoA respiratory kinetics that precede development of diabetic cardiomyopathy are prevented by resveratrol in ZDF rats.
Beaudoin MS, Perry CG, Arkell AM, Chabowski A, Simpson JA, Wright DC, Holloway GP.


??-Lapachone ameliorates lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice.
Jeong MH, Tran NK, Kwak TH, Park BK, Lee CS, Park TS, Lee YH, Park WJ, Yang DK.


Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation.
Chow JD, Lawrence RT, Healy ME, Dominy JE, Liao JA, Breen DS, Byrne FL, Kenwood BM, Lackner C, Okutsu S, Mas VR, Caldwell SH, Tomsig JL, Cooney GJ, Puigserver PB, Turner N, James DE, Vill??n J, Hoehn KL.


Detecting apoptosis in Drosophila tissues and cells.
Sarkissian T, Timmons A, Arya R, Abdelwahid E, White K.


Selective propagation of functional mitochondrial DNA during oogenesis restricts the transmission of a deleterious mitochondrial variant.
Hill JH, Chen Z, Xu H.


Complex changes in the liver mitochondrial proteome of short chain acyl-CoA dehydrogenase deficient mice.
Wang W, Mohsen AW, Uechi G, Schreiber E, Balasubramani M, Day B, Michael Barmada M, Vockley J.


Tissue-specific loss of DARS2 activates stress responses independently of respiratory chain deficiency in the heart.
Dogan SA, Pujol C, Maiti P, Kukat A, Wang S, Hermans S, Senft K, Wibom R, Rugarli EI, Trifunovic A.


Tumor necrosis factor-?? impairs oligodendroglial differentiation through a mitochondria-dependent process.
Bonora M, De Marchi E, Patergnani S, Suski JM, Celsi F, Bononi A, Giorgi C, Marchi S, Rimessi A, Duszy??ski J, Pozzan T, Wieckowski MR, Pinton P.


Dysregulation of ubiquitin homeostasis and ??-catenin signaling promote spinal muscular atrophy.
Wishart TM, Mutsaers CA, Riessland M, Reimer MM, Hunter G, Hannam ML, Eaton SL, Fuller HR, Roche SL, Somers E, Morse R, Young PJ, Lamont DJ, Hammerschmidt M, Joshi A, Hohenstein P, Morris GE, Parson SH, Skehel PA, Becker T, Robinson IM, Becker CG, et al.


Hydroxytyrosol ameliorates oxidative stress and mitochondrial dysfunction in doxorubicin-induced cardiotoxicity in rats with breast cancer.
Granados-Principal S, El-Azem N, Pamplona R, Ramirez-Tortosa C, Pulido-Moran M, Vera-Ramirez L, Quiles JL, Sanchez-Rovira P, Naud?? A, Portero-Otin M, Perez-Lopez P, Ramirez-Tortosa M.


Intermittent and continuous high-intensity exercise induce similar acute but different chronic muscle training adaptations.
Cochran AJ, Percival ME, Tricarico S, Little JP, Cermak N, Gillen JB, Tarnopolsky MA, Gibala MJ.


SDHA mutations causing a multisystem mitochondrial disease: novel mutations and genetic overlap with hereditary tumors.
Renkema GH, Wortmann SB, Smeets RJ, Venselaar H, Antoine M, Visser G, Ben-Omran T, van den Heuvel LP, Timmers HJ, Smeitink JA, Rodenburg RJ.


Mutations in the SPG7 gene cause chronic progressive external ophthalmoplegia through disordered mitochondrial DNA maintenance.
Pfeffer G, Gorman GS, Griffin H, Kurzawa-Akanbi M, Blakely EL, Wilson I, Sitarz K, Moore D, Murphy JL, Alston CL, Pyle A, Coxhead J, Payne B, Gorrie GH, Longman C, Hadjivassiliou M, McConville J, Dick D, Imam I, Hilton D, Norwood F, Baker MR, et al.


Bulk autophagy, but not mitophagy, is increased in cellular model of mitochondrial disease.
Mor??n M, Delmiro A, Bl??zquez A, Ugalde C, Arenas J, Mart??n MA.


Quantitative Proteomics of Synaptic and Nonsynaptic Mitochondria: Insights for Synaptic Mitochondrial Vulnerability.
Stauch KL, Purnell PR, Fox HS.


Atypical Friedreich ataxia in patients with FXN p.R165P point mutation or comorbid hemochromatosis.
Ygland E, Taroni F, Gellera C, Caldarazzo S, Duno M, Soller M, Puschmann A.


Expression of oxidored nitro domain-containing protein 1(NOR1) impairs nasopharyngeal carcinoma cells adaptation to hypoxia and inhibits PDK1 expression.
Xiang B, Yi M, Li W, Wang W, Zheng P, Li X, Li G.


Mitochondrial complex IV deficiency, caused by mutated COX6B1, is associated with encephalomyopathy, hydrocephalus and cardiomyopathy.
Abdulhag UN, Soiferman D, Schueler-Furman O, Miller C, Shaag A, Elpeleg O, Edvardson S, Saada A.


Drp1 stabilizes p53 on the mitochondria to trigger necrosis under oxidative stress conditions in??vitro and in??vivo.
Guo X, Sesaki H, Qi X.


Mitochondrial dysfunction induced by frataxin deficiency is associated with cellular senescence and abnormal calcium metabolism.
Bolinches-Amor??s A, Moll?? B, Pla-Mart??n D, Palau F, Gonz??lez-Cabo P.


Mitochondrial leucine tRNA level and PTCD1 are regulated in response to leucine starvation.
Schild C, Hahn D, Schaller A, Jackson CB, Rothen-Rutishauser B, Mirkovitch J, Nuoffer JM.


Epidermal nerve fiber density, oxidative stress, and mitochondrial haplogroups in HIV-infected Thais initiating therapy.
Hulgan T, Levinson R, Gerschenson M, Phanuphak N, Ananworanich J, Teeratakulpisarm N, Jadwattanakul T, Libutti DE, Fink H, McArthur JC, Ebenezer GJ, Hauer P, Murdock D, Shikuma CM, Samuels DC; for the SEARCH 003 Study Team.


Amino acid starvation has opposite effects on mitochondrial and cytosolic protein synthesis.
Johnson MA, Vidoni S, Durigon R, Pearce SF, Rorbach J, He J, Brea-Calvo G, Minczuk M, Reyes A, Holt IJ, Spinazzola A.


Neuroglobin mitigates mitochondrial impairments induced by acute inhalation of combustion smoke in the mouse brain.
Gorgun FM, Zhuo M, Singh S, Englander EW.


Albumin-bound fatty acids but not albumin itself alter redox balance in tubular epithelial cells and induce a peroxide-mediated redox-sensitive apoptosis.
Ruggiero C, Elks CM, Kruger C, Cleland E, Addison K, Noland RC, Stadler K.


Modulating effect of SIRT1 activation induced by resveratrol on Foxo1-associated apoptotic signalling in senescent heart.
Sin TK, Yu AP, Yung BY, Yip SP, Chan LW, Wong CS, Ying M, Rudd JA, Siu PM.


Regulation of the Mitochondrial Permeability Transition Pore by the Outer Membrane does not Involve the Peripheral Benzodiazepine Receptor (TSPO).
Sileikyte J, Blachly-Dyson E, Sewell R, Carpi A, Menabo R, Di Lisa F, Ricchelli F, Bernardi P, Forte M.


Deoxynucleoside stress exacerbates the phenotype of a mouse model of mitochondrial neurogastrointestinal encephalopathy.
Garcia-Diaz B, Garone C, Barca E, Mojahed H, Gutierrez P, Pizzorno G, Tanji K, Arias-Mendoza F, Quinzii CM, Hirano M.


Nicotinamide Nucleotide Transhydrogenase (Nnt) Links the Substrate Requirement in Brain Mitochondria for Hydrogen Peroxide Removal to the Thioredoxin/Peroxiredoxin (Trx/Prx) System.
Lopert P, Patel M.


Common and Novel TMEM70 Mutations in a Cohort of Italian Patients with Mitochondrial Encephalocardiomyopathy.
Diodato D, Invernizzi F, Lamantea E, Fagiolari G, Parini R, Menni F, Parenti G, Bollani L, Pasquini E, Donati MA, Cassandrini D, Santorelli FM, Haack TB, Prokisch H, Ghezzi D, Lamperti C, Zeviani M.


Estradiol stimulates mitochondrial biogenesis and adiponectin expression in skeletal muscle.
Capllonch-Amer G, Sbert-Roig M, Galm??s-Pascual BM, Proenza AM, Llad?? I, Gianotti M, Garc??a-Palmer FJ.


Adipose tissue insulin resistance due to loss of PI3K p110?? leads to decreased energy expenditure and obesity.
Nelson VL, Jiang YP, Dickman KG, Ballou LM, Lin RZ.


Impairments in mitochondrial palmitoyl-CoA respiratory kinetics that precede development of diabetic cardiomyopathy are prevented by resveratrol in ZDF rats.
Beaudoin MS, Perry CG, Arkell AM, Chabowski A, Simpson JA, Wright DC, Holloway GP.


Hypoxia differentially regulates muscle oxidative fiber type and metabolism in a HIF-1??-dependent manner.
Slot IG, Schols AM, Vosse BA, Kelders MC, Gosker HR.


MuRF1 activity is present in cardiac mitochondria and regulates reactive oxygen species production in vivo.
Mattox TA, Young ME, Rubel CE, Spaniel C, Rodr??guez JE, Grevengoed TJ, Gautel M, Xu Z, Anderson EJ, Willis MS.


Activation of AMPK??2 is not crucial for mitochondrial uncoupling-induced metabolic effects but required to maintain skeletal muscle integrity.
Ost M, Werner F, Dokas J, Klaus S, Voigt A.


ATAD3 is a limiting factor in mitochondrial biogenesis and adipogenesis of white adipocyte-like 3T3-L1 cells.
Li S, Yao Y, Xu R, Pesenti S, Cottet-Rousselle C, Rieusset J, Tokarska-Schlattner M, Liao K, Schlattner U, Rousseau D.


Modeling of antigenomic therapy of mitochondrial diseases by mitochondrially addressed RNA targeting a pathogenic point mutation in mitochondrial DNA.
Tonin Y, Heckel AM, Vysokikh M, Dovydenko I, Meschaninova M, R??tig A, Munnich A, Venyaminova A, Tarassov I, Entelis N.


Mitochondrial SIRT3 and its target glutamate dehydrogenase are altered in follicular cells of women with reduced ovarian reserve or advanced maternal age.
Pacella-Ince L, Zander-Fox DL, Lane M.


Physical exercise prevents and mitigates non-alcoholic steatohepatitis-induced liver mitochondrial structural and bioenergetics impairments.
Gon??alves IO, Passos E, Rocha-Rodrigues S, Diogo CV, Torrella JR, Rizo D, Viscor G, Santos-Alves E, Marques-Aleixo I, Oliveira PJ, Ascens??o A, Magalh??es J.


Frataxin silencing inactivates mitochondrial Complex I in NSC34 motoneuronal cells and alters glutathione homeostasis.
Carletti B, Piermarini E, Tozzi G, Travaglini L, Torraco A, Pastore A, Sparaco M, Petrillo S, Carrozzo R, Bertini E, Piemonte F.


Prevention and reversal of severe mitochondrial cardiomyopathy by gene therapy in a mouse model of Friedreich's ataxia.
Perdomini M, Belbellaa B, Monassier L, Reutenauer L, Messaddeq N, Cartier N, Crystal RG, Aubourg P, Puccio H.


Cellular consequences of oxidative stress in riboflavin responsive multiple acyl-CoA dehydrogenation deficiency patient fibroblasts.
Cornelius N, Corydon TJ, Gregersen N, Olsen RK.


Mitochondrial proteolytic stress induced by loss of mortalin function is rescued by Parkin and PINK1.
Burbulla LF, Fitzgerald JC, Stegen K, Westermeier J, Thost AK, Kato H, Mokranjac D, Sauerwald J, Martins LM, Woitalla D, Rapaport D, Riess O, Proikas-Cezanne T, Rasse TM, Kr??ger R.


Development of 3-Phenyl-N-(2-(3-phenylureido)ethyl)-thiophene-2-sulfonamide Compounds as Inhibitors of Antiapoptotic Bcl-2 Family Proteins.
Yang C, Chen S, Zhou M, Li Y, Li Y, Zhang Z, Liu Z, Ba Q, Li J, Wang H, Yan X, Ma D, Wang R.


The NFL-TBS.40-63 Anti-Glioblastoma Peptide Disrupts Microtubule and Mitochondrial Networks in the T98G Glioma Cell Line.
Rivalin R, Lepinoux-Chambaud C, Eyer J, Savagner F.


Enhanced defense against mitochondrial hydrogen peroxide attenuates age-associated cognition decline.
Chen L, Na R, Ran Q.


Mitochondrial dysfunction induced by frataxin deficiency is associated with cellular senescence and abnormal calcium metabolism.
Bolinches-Amor??s A, Moll?? B, Pla-Mart??n D, Palau F, Gonz??lez-Cabo P.


VARS2 and TARS2 Mutations in Patients with Mitochondrial Encephalomyopathies.
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The Drosophila effector caspase Dcp-1 regulates mitochondrial dynamics and autophagic flux via SesB.
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The arginine methyltransferase NDUFAF7 is essential for complex I assembly and early vertebrate embryogenesis.
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PINK1-Parkin Pathway Activity Is Regulated by Degradation of PINK1 in the Mitochondrial Matrix.
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New MT-ND1 pathologic mutation for Leber hereditary optic neuropathy.
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Mechanical unloading promotes myocardial energy recovery in human heart failure.
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Photobiomodulation with near infrared light mitigates Alzheimer's disease-related pathology in cerebral cortex - evidence from two transgenic mouse models.
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Aging synaptic mitochondria exhibit dynamic proteomic changes while maintaining bioenergetic function.
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Mitochondrial complex I deficiency enhances skeletal myogenesis but impairs insulin signaling through SIRT1 inactivation.
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Addressing RNA integrity to determine the impact of mitochondrial DNA mutations on brain mitochondrial function with age.
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Diisopropylamine dichloroacetate, a novel pyruvate dehydrogenase kinase 4 inhibitor, as a potential therapeutic agent for metabolic disorders and multiorgan failure in severe influenza.
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Adipose tissue insulin resistance due to loss of PI3K p110?? leads to decreased energy expenditure and obesity.
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Astrocyte-dependent protective effect of quetiapine on GABAergic neuron is associated with the prevention of anxiety-like behaviors in aging mice after long-term treatment.
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Early alterations in energy metabolism in the hippocampus of APPSwe/PS1dE9 mouse model of Alzheimer's disease.
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Megakaryocytic Differentiation of K562 Cells Induced by PMA Reduced the Activity of Respiratory Chain Complex IV.
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Benzothiophene Carboxylate Derivatives as Novel Allosteric Inhibitors of Branched-chain ??-Ketoacid Dehydrogenase Kinase.
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MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin.
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Mitochondrial calcium uniporter activity is dispensable for MDA-MB-231 breast carcinoma cell survival.
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Fluorescence staining of mitochondria for morphology analysis in Saccharomyces cerevisiae.
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Fluorescence staining of mitochondria for morphology analysis in Saccharomyces cerevisiae.
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Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies.
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Msp1/ATAD1 maintains mitochondrial function by facilitating the degradation of mislocalized tail-anchored proteins.
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