All Research Kits


MS101 Complex I Immunocapture Kit
250 g, 500 g or 750 g monoclonal antibody irreversibly crosslinked to protein G-agarose beads which can immunocapture ~60 g, ~120 g or ~180 g respectively of Complex I (NADH dehdydrogenase) from heart mitochondria.

MS130 Dipstick Assay Kit for Complex I Activity
This kit contains 30 or 60 dipsticks and necessary components for quantitative analysis of NADH ubiquinone oxidoreductase activity in human, bovine, rat, and mouse samples.

MS131 Dipstick Assay Kit for Human Complex I Quantity
This kit contains 30 or 60 dipsticks and necessary components for quantitative analysis of NADH ubiquinone oxidoreductase in human and bovine samples.

MS133 Dipstick Assay Kit for Rodent Complex I Quantity
This kit contains 30 or 60 dipsticks and necessary components for quantitative analysis of NADH ubiquinone oxidoreductase in mouse and rat samples.

MS141 Rapid Microplate Assay Kit for Complex I Activity
A rapid activity microplate kit that is used to determine the activity of Complex I in a human sample with speed and simplicity. Includes buffers, detergent, substrates, and 96-well microplate with monoclonal antibody pre-bound to the wells of the plate, allowing for a stream-lined assay.

MS142 Rapid Microplate Assay Kit for Complex I Quantity
A rapid activity microplate kit that is used to determine the amount of Complex I in a human sample with speed and simplicity. Includes buffers, detergent, substrates, and 96-well microplate with monoclonal antibody pre-bound to the wells of the plate, allowing for a stream-lined assay.

MS201 Complex II Immunocapture Kit
250 g, 500 g or 750 g monoclonal antibodies irreversibly crosslinked to protein G-agarose beads which can immunocapture ~13 g, ~26 g or ~39 g respectively of Complex II from heart mitochondria.

MS202 Human Complex II Cocktail
Contains a total of 300 g or 600 g of antibodies and is a pre-mixed solution of 3 monoclonal antibodies against Complex II subunits 70 kDa Fp, 30 kDa Ip along with an antibody against Complex V α as a control. This cocktail can be used to verify isolated Complex II purity or to conveniently determine the levels of 2 of the 4 Complex II subunits in patient cell lines relative to the control protein (Complex V α).

MS301 Complex III Immunocapture Kit
250 g, 500 g or 750 g monoclonal antibodies irreversibly crosslinked to protein G-agarose beads which can immunocapture ~25 g, ~50 g or ~75 g respectively of Complex III from heart mitochondria.

MS401 Complex IV Immunocapture Kit
250 g, 500 g or 750 g monoclonal antibodies irreversibly crosslinked to protein G-agarose beads which can immunocapture ~25 g, ~50 g or ~75 g respectively of Complex IV from heart mitochondria.

MS402 Complex IV Immunocapture Kit for Rodent
250 g, 500 g or 750 g monoclonal antibodies irreversibly crosslinked to protein G-agarose beads which can immunocapture ~25 g, ~50 g or ~75 g respectively of Complex IV from heart mitochondria. The Complex IV immunocapture kit allows isolation of the cytochrome c oxidase complex (E.C. 1.9.3.1) from small amounts of rat or mouse tissue.

MS430 Dipstick Assay Kit for Human Complex IV Activity
This kit contains 30 or 60 dipsticks and necessary components for quantitative analysis of cytochrome c oxidase activity in human and bovine samples.

MS431 Dipstick Assay Kit for Human Complex IV Quantity
This kit contains 30 or 60 dipsticks and necessary components for quantitative analysis of cytochrome c oxidase in human and bovine samples.

MS432 Dipstick Assay Kit for Rodent Complex IV Activity
This kit contains 30 or 60 dipsticks and necessary components for quantitative analysis of cytochrome c oxidase activity in mouse and rat samples.

MS441 Rapid Microplate Assay Kit for Human Complex IV Activity
A rapid activity microplate kit that is used to determine the activity of cytochrome c oxidase in a human sample with greater speed and simplicity. Includes buffers, detergent, substrates, and 96-well microplate with monoclonal antibody pre-bound to the wells of the plate, allowing for a stream-lined assay.

MS442 Rapid Microplate Assay Kit for Human Complex IV Quantity
A rapid activity microplate kit that is used to determine the amount of cytochrome c oxidase in a human sample with greater speed and simplicity. Includes buffers, detergent, substrates, and 96-well microplate with monoclonal antibody pre-bound to the wells of the plate, allowing for a stream-lined assay.

MS443 Rapid Microplate Assay Kit for Human Complex IV Activity and Quantity (Multiplexing)
A 96-well multiplexing microplate kit that is used to determine both the activity and quantity of cytochrome c oxidase in a human sample with greater speed and simplicity. Includes buffers, detergent, substrates, and 96-well microplate with monoclonal antibody pre-bound to the wells of the plate, allowing for a stream-lined assay.

MS444 Rapid Microplate Assay Kit for Mouse Complex IV Activity
A 96-well activity microplate kit that is used to determine the activity of cytochrome c oxidase in a mouse sample with greater speed and simplicity. Includes buffers, detergent, substrates, and 96-well microplate with monoclonal antibody pre-bound to the wells of the plate, allowing for a stream-lined assay.

MS445 Rapid Microplate Assay Kit for Mouse Complex IV Quantity
A 96-well activity microplate kit that is used to determine the amount of cytochrome c oxidase in a mouse sample with greater speed and simplicity. Includes buffers, detergent, substrates, and 96-well microplate with monoclonal antibody pre-bound to the wells of the plate, allowing for a stream-lined assay.

MS446 Rapid Microplate Assay Kit for Mouse Complex IV Activity and Quantity (Multiplexing)
A 96-well multiplexing microplate kit that is used to determine both the activity and quantity of cytochrome c oxidase in a mouse sample with greater speed and simplicity. Includes buffers, detergent, substrates, and 96-well microplate with monoclonal antibody pre-bound to the wells of the plate, allowing for a stream-lined assay.

MS447 Rapid Microplate Assay Kit for Rat Complex IV Activity
A 96-well activity microplate kit that is used to determine the activity of cytochrome c oxidase in a rat sample with greater speed and simplicity. Includes buffers, detergent, substrates, and 96-well microplate with monoclonal antibody pre-bound to the wells of the plate, allowing for a stream-lined assay.

MS501 ATP synthase (Complex V) Immunocapture Kit
250 g, 500 g or 750 g of monoclonal antibodies irreversibly crosslinked to protein G-agarose beads which can immunocapture ~125 g, ~250 g or ~500 g respectively of ATP synthase (Complex V) from heart mitochondria.

MS541 Rapid Microplate Assay Kit for ATP synthase (Complex V) Activity
A rapid activity microplate kit that is used to determine the activity of ATP synthase in human and rat samples with great speed and simplicity. Includes buffers, detergent, lipid mix, substrates and 96-well microplate with monoclonal antibody pre-bound to the wells of the plate, allowing for a stream-lined assay.

MS542 Rapid Microplate Assay Kit for ATP synthase (Complex V) Quantity
A rapid activity microplate kit that is used to determine the amount of ATP synthase in human and rat samples with great speed and simplicity. Includes buffers, detergent, substrates, and 96-well microplate with monoclonal antibody pre-bound to the wells of the plate, allowing for a stream-lined assay.

MS543 Rapid Microplate Assay Kit for ATP synthase (Complex V) Activity and Quantity (Multiplexing)
A 96-well multiplexing microplate kit that is used to determine both the activity and quantity of ATP synthase in human and rat samples with great speed and simplicity. Includes buffers, detergent, lipid mix, substrates, and 96-well microplate with monoclonal antibody pre-bound to the wells of the plate, allowing for a stream-lined assay.

MS601 MitoProfile Human Total OXPHOS Complexes Detection Kit
Contains a total of 360 g or 720 g of antibodies and is a premixed solution of 5 monoclonal antibodies against a subunit of each of the 5 OXPHOS complexes. Human heart mitochondria are also included as a Western blotting control.

MS602 MitoProfile OXPHOS/PDH Immunocytochemistry Kit
A cocktail of 220 g antibodies comprised of six mAbs packaged individually. Each antibody is against a labile subunit of each of the 5 OXPHOS complexes and PDH. Each mAb is provided in a 50 l aliquot at a 200x concentration, to allow reconstitution of each mAb in 10 ml working volume.

MS602a MitoProfile OXPHOS/PDH Immunocytochemistry Kit
Includes the same components as MS602 (above), but additionally contains 60 g mAb to porin, and 120 g to Complex V α subunit, and the required secondary antibodies for simultaneous 2 dye staining of samples.

MS603 MitoProfile Total OXPHOS Complexes Blue Native Blotting Detection Kit
A cocktail of mAbs which allows the rapid and highly sensitive detection of OXPHOS components from very small sample amounts. This cocktail allows the simultaneous analysis of the assembly state of all 5 OXPHOS complexes from a single patient sample. Bovine heart mitochondria are also included as a control sample.

MS604 MitoProfile Rodent Total OXPHOS Complexes Detection Kit
Contains a total of 300 g or 600 g of antibodies and is a premixed solution of 5 monoclonal antibodies against a subunit of each of the 5 OXPHOS complexes in mitochondrial preparations from rodent sources. Mouse brain mitochondria are also included as a Western blotting control.

MS620 MitoProfile Mitochondria Membrane Integrity Kit
Contains 255 g of 5 mAbs against representative proteins for each of the primary structures of the mitochondrion: the outer membrane, the intermembrane space, the inner membrane, and the matrix space. This kit is useful in Western blotting to evaluate the structural integrity of isolated mitochondria. Human Heart Mitochondria are provided as standard control, mitochondria from other species and tissue available.

MS631 MitoProfile Biogenesis Dipstick Assay Kit
MS631 is a rapid and simple test for determining whether mitochondrial biogenesis has been up-regulated or down-regulated in human samples. The assay works on very small amounts of sample material, including cheek swabs or single drops of blood, and results can be generated in under 30 minutes.

MS641 MitoProfile Biogenesis Microplate Assay Kit
MS641 is a high-throughput test for determining whether mitochondrial biogenesis has been up-regulated or down-regulated in human samples. The assay works on very small amounts of sample material and is suitable for screening of antiviral and antibiotic drugs.

MS740 Rapid Microplate Assay Kit for Human Mitochondrial Trifunctional Protein (MTP)
This kit is used to determine the assembled enzyme quantity of Mitochondrial Trifunctional Protein (MTP) in a human sample with speed and simplicity.

MS741 Dipstick Assay Kit for Human Mitochondrial Trifunctional Protein (MTP)
Contains 30 or 60 dipsticks and necessary components to quantify the amount of the Mitochondrial Trifunctional Protein (MTP) from human sample material.

MSA01 ANT Immunocapture Kit
250 g monoclonal antibody irreversibly crosslinked to protein G-agarose beads which can immunocapture ANT from heart mitochondria.

MSA07 ApoTrack™ Apoptosis Detection Kit for Immunocytochemistry
MSA07 detects apoptotic cells with high specificity. It contains an anti-cytochrome c monoclonal antibody (50 g) and the appropriate isotype-specific secondary antibody (50 g) which has a fluorescein fluorophore conjugated to it. The kit also contains an anti-Complex Vα monoclonal antibody (50 g) and the appropriate Texas Red fluorophore-conjugated isotype-specific secondary antibody (50 g). Complex V serves as a mitochondrial marker in healthy and apoptotic cells.

MSA11 ApoTrack™ Cytochrome c Apoptosis Kit
Contains 180 g of premixed cocktail of 4 monoclonal antibodies and necessary buffers and detergent allowing for a rapid method to measure the fraction of cytochrome c released from mitochondria into the cytosol during apoptosis. Human heart mitochondria are included as a Western blotting control.

MSA12 ApoTrack™ Apoptosis Detection Kit for Western blotting
Contains 180 g of premixed cocktail of 4 monoclonal antibodies that allows detection of cytochrome c in the cytoplasmic and mitochondria-containing fractions by Western Blot analysis to determine the proportion of released cytochrome c from mitochondria to cytoplasm. Human heart mitochondria are also included as a Western blotting control.

MSA31 Dipstick Assay Kit for Apoptosis-Inducing Factor (AIF) Quantity
This kit contains 30 or 60 dipsticks and necessary components to quantify the amount of Apoptosis-Inducing Factor (AIF) from human sample material.

MSA41 Rapid Microplate Assay Kit for Cytochrome c Quantity
A 96-well activity microplate kit that is used to determine the amount of cytochrome c in a human, bovine, mouse, or rat samples. Includes detergent, substrates, and 96-well microplate with monoclonal antibody pre-bound to the wells of the plate, allowing for a stream-lined assay.

MSA42 Rapid Microplate Assay Kit for Apoptosis-Inducing Factor (AIF)
AIF is a flavoprotein (67 kDa) localized in the inter-membrane space. It is a multi-functional protein with a vital oxidoreductase function (required for cell survival), an anti-oxidant activity, an assembly function in Complex I (NADH-ubiquinone oxidoreductase complex) formation and an apoptogenic function. AIF has a major role in the caspase-independent apoptosis process. It translocates to the nucleus after mitochondrial release, leading to chromatin condensation and DNA fragmentation.

MSF31 Dipstick Assay Kit for Frataxin
This kit contains 30 or 60 dipsticks and necessary components for quantitative analysis of human frataxin protein levels.

MSF41 Rapid Microplate Assay Kit for Frataxin
Frataxin is a nuclear-encoded mitochondrial protein. In humans the gene is localized on chromosome 9 and is highly conserved during evolution. The gene is expressed in every cell, although in varying levels in different tissues and during development. Friedreich's Ataxia (FRDA) is an inherited recessive neurodegenerative disorder caused by decreased expression levels of frataxin. FRDA is the most common inherited ataxia and it causes progressive damage to the nervous system, resulting in symptoms ranging from muscle weakness and speech problems to heart disease. About one in 50,000 people in the United States have Friedreich's Ataxia.

MSP01 PDH Immunocapture Kit
250 g monoclonal antibody irreversibly crosslinked to protein G-agarose beads which can immunocapture ~13 g of PDH complex from heart mitochondria.

MSP02 MitoProfile PDH Subunit Western Blotting Kit
Contains a total of 150 g or 300 g respectively of monoclonal antibodies reactive against PDH subunits.

MSP18 Rapid Microplate Assay Kit for PDH Activity
A rapid activity microplate kit that is used to determine the activity of PDH in a human, bovine, mouse, or rat sample with greater speed and simplicity. Includes buffer, detergent, reagent mix, and 96-well microplate with monoclonal antibody pre-bound to the wells of the plate, allowing for a stream-lined assay.

MSP19 Rapid Microplate Assay Kit for PDH Quantity
A 96-well activity microplate kit that is used to determine the amount of PDH in a human, bovine, mouse, or rat sample. Includes buffers, detergent, substrates, and 96-well microplate with monoclonal antibody pre-bound to the wells of the plate, allowing for a stream-lined assay.

MSP20 Rapid Mitcroplate Assay Kit for PDH Activity (Combo)
A combination of MSP18 and MSP19 microplate assay kits that are used to determine both the activity and quantity of PDH in a human, bovine, mouse, or rat sample. Includes buffers, detergent, reagent mix, substrates, and 96-well microplate with monoclonal antibody pre-bound to the wells of the plate, allowing for a stream-lined assay.

MSP30 Dipstick Assay Kit for PDH Activity
This kit contains 30 or 60 dipsticks and necessary components for quantitative analysis of PDH activity in human, bovine, mouse, rat, and pig samples.

MSP31 Dipstick Assay Kit for PDH Quantity
This kit contains 30 or 60 dipsticks and necessary components for quantitative analysis of PDH in human, bovine, mouse, and rat samples.

MS850 Mitochondria Isolation Kit for Rodent Tissue
Contains sufficient reagents for up to 10 benchtop mitochondria isolations from hard or soft rodent tissues. Isolated mitochondria can be analyzed by Western Blotting, Immunocapture, or Activity assay.

MS851 Mitochondria Isolation Kit for Rodent Tissue (with Dounce Homogenizer)
Contains sufficient reagents and a homogenizer for up to 10 benchtop mitochondria isolations from hard or soft rodent tissues. Isolated mitochondria can be analyzed by Western Blotting, Immunocapture, or Activity assay.

MS852 Mitochondria Isolation Kit for Cultured Cells
Contains sufficient reagents for up to 20 benchtop mitochondria isolations from human cultured cells. Isolated mitochondria can be analyzed by Western Blotting, Immunocapture, or Activity assay.

MS853 Mitochondria Isolation Kit for Cultured Cells (with Dounce Homogenizer)
Contains sufficient reagents and a homogenizer for up to 20 benchtop mitochondria isolations from human cultured cells. Isolated mitochondria can be analyzed by Western Blotting, Immunocapture, or Activity assay.


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