MS601 is a mAb cocktail optimized for the detection of a subunit from each of the 5 OXPHOS subunits. This kit is an already mixed solution containing 5 mAbs, one each against a 20 kDa subunit of Complex I, 30 kDa non-heme iron subunit of succinate dehydrogenase (Complex II), core protein 2 of Complex III, subunit II of cytochrome c oxidase (Complex IV) and the a subunit of the ATP synthase (Complex V).

These polypeptides can be well separated by SDS-PAGE. The OXPHOS mAb cocktail provides an important analysis of the purity of isolated mitochondria or individual complexes. Also this cocktail allows the rapid detection of the decrease of an individual OXPHOS complex in a sample relative to control. In addition 50 µg of SDS-dissociated human mitochondria are supplied for use as an Western blotting control sample.