Jump to Products:
• Monoclonal Antibodies >



Short-chain specific acyl-CoA dehydrogenase,

mitochondrial (SCAD)


UniProt Number: P16219
Alternate Names: Butyryl-CoA dehydrogenase, ACADS
Structure and Function: Acyl-CoA dehydrogenases are a class of enzymes that catalyze the initial step in each cycle of fatty acid β-oxidation in the mitochondria of cells. Their action results in the introduction of a trans double-bond between C2 and C3 of the acyl-CoA thioester substrate. Acyl-CoA dehydrogenases can be categorized into three distinct groups based on their specificity for short-, medium-, or long-chain fatty acid acyl-CoA substrates. Short chain specific acyl-CoA dehydrogenases target fatty acids of 4-6 C length.
Disease Associations: Defects in ACADS are the cause of acyl-CoA dehydrogenase short-chain deficiency (ACADSD) [MIM:201470]. It is an autosomal recessive disorder resulting in acute acidosis and muscle weakness in infants, and a form of lipid-storage myopathy in adults.


Monoclonal Antibodies
Cat. No. Name Reactivity Apps. Amount
MS784 SCAD Antibody Human WB, ICC, ICE 100 µg



Browse Products By:
Product Search:




Related Pathways:



Fatty Acid Oxidation (Mitochondrial)


Subscribe to MitoNews
MitoNews is a free periodic annotated review of important publications in mitochondria and metabolic research.

MitoNews Latest Issue
Volume 11 Issue 01 (February 2015)

MitoNews Archives


Sales & Customer Support:
1-888-772-2226

[email protected]

© 2004-2022 MitoSciences Inc, an Abcam company. All rights reserved.