MSA08 Porin monoclonal antibody
for yeast
$295.00 (100 µg)
Please contact us for volume discounts.
This product can also be ordered as part of a sample pack.
Brief Description & Uses
100 µg of monoclonal antibody reactive against porin for use in Western blotting applications.
The channel-forming protein porin (also called the voltage dependent
anion channel, VDAC) is involved in both aerobic metabolism and
apoptotic processes. Porin is localized in the outer membrane of
mitochondria where it forms the primary pathway of metabolites across
the membrane. Porin can also serve as a binding site for enzymes or a
regulatory molecule.
Multiple isoforms of porin have been identified in mammals and plants. In Saccharomyces cerevisiae one isoform showing properties that are conserved among other species has been identified (POR1). The second gene (POR2) discovered does not exhibit the channel forming activity. However, yeast strains in which the POR1 gene has been deleted (Dpor1)
can still grow on yeast media containing a nonfermentable carbon
source. Thus, the second protein present can partially substitute for
that function in a non-channel dependent way.
Specifications
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Product:
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Porin monoclonal antibody
for yeast
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Catalog #:
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MSA08
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Lot #:
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Clone ID:
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16G9E6BC4
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Host Species and Isotype:
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Mouse IgG1, κ
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Immunogen:
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VDAC-1 from S. cerevisiae, denatured in SDS-PAGE
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Concentration:
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1 mg/ml in Hepes-Buffered Saline (HBS) with 0.02% azide as a preservative.
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Purity:
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Near homogeneity as judged by SDS-PAGE. The antibodies were produced in vitro using hybridomas grown in serum-free medium, and then purified by biochemical fractionation.
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Suggested Working Concentration:
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0.1 µg/ml for Western blotting
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Applications:
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Western blotting
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Antigen Species Cross-Reactivity:
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S. cerevisiae
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Storage:
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4°C
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Country of Origin:
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USA
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Product References
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References for Porin
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