MS419 Complex IV subunit II (Cox2p)
monoclonal antibody for yeast
$295.00 (100 µg)
Please contact us for volume discounts.
This product can also be ordered as part of a sample pack.
Brief Description & Uses
100 µg of monoclonal antibody reactive against Complex IV subunit II for use in Western blotting.
In yeast Saccharomyces cerevisiae, cytochrome c
oxidase (COX) is composed of 11 subunits, three of which are encoded in
the mitochondrial genome (Cox1p, Cox2p and Cox3p). These three large
subunits are transmembrane proteins that form the catalytic core of the
enzyme.
The remaining subunits (Cox4p-Cox9p) are nuclear encoded and
transported into the mitochondria after translation. Although the
specific functions of the subunits are not completely understood, they
are known to be involved in the assembly of the enzyme. Studies with
yeast strains carrying null mutations in these subunits have shown
complete loss of COX activity, suggesting that the subunits play a
crucial role in assembly and stability of the enzyme. The COX assembly
process is conserved between human and yeast.
Specifications
|
Product:
|
Complex IV subunit II (Cox2p)
monoclonal antibody for yeast
|
|
Catalog #:
|
MS419
|
|
Lot #:
|
|
|
Clone ID:
|
4B12A5
|
|
Host Species and Isotype:
|
Mouse IgG2a, κ
|
|
Immunogen:
|
|
|
Concentration:
|
1 mg/ml in Dulbecco’s Phosphate-Buffered Saline (PBS) with 0.02% azide as a preservative.
|
|
Purity:
|
Near homogeneity as judged by SDS-PAGE. The antibodies were produced in vitro using hybridomas grown in serum-free medium, and then purified by biochemical fractionation.
|
|
Suggested Working Concentration:
|
2.0 µg/ml for Western blotting
|
|
Applications:
|
Western blotting
|
|
Antigen Species Cross-Reactivity:
|
S. cerevisiae
|
|
Storage:
|
4°C
|
|
Country of Origin:
|
USA
|
Product References
There are no references currently posted for this product.
Have you published research using this product?
Let us know and earn a $100.00 discount on your next purchase.
References for Complex IV subunit II (Cox2p)
There are no references currently posted for this product.
Images
|
CART
