MS201c Complex II Immunocapture
monoclonal antibody
$295.00 (100 µg)
Please contact us for volume discounts.
Brief Description & Uses
100 µg monoclonal antibody which can immunocapture ~5 µg of Complex II from heart mitochondria. Isolated mitochondria are available from several species for use as control samples. To see the complete list of control samples available from MitoSciences, click here.
The Complex II immunocapture kit allows isolation of the succinate dehydrogenase complex (E.C. 1.3.5.1) from small amounts of tissue. This facilitates subsequent analysis of assembly state, activity and the extent of post translational modifications including oxidative damage that occur with aging. Uses for the Complex II immunocapture kit include research on aging genetic mitochondrial disease, and various cancers due to mutations in this enzyme complex such as paragangliomas and phaeo-chromocytomas.
Specifications
Product:
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Complex II Immunocapture
monoclonal antibody
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Catalog #:
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MS201c
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Lot #:
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Clone ID:
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4H12BG12AG2
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Host Species and Isotype:
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Mouse IgG1, κ
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Immunogen:
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Bovine Heart Complex II, with traces of Complex III
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Concentration:
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1 mg/ml in Dulbecco’s Phosphate-Buffered Saline (PBS) with 0.02% azide as a preservative.
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Purity:
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Near homogeneity as judged by SDS-PAGE. The antibodies were produced in vitro using hybridomas grown in serum-free medium, and then purified by biochemical fractionation.
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Suggested Working Concentration:
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100 µg mAb can capture at least 5 µg complex II from 1 mg solubilized bovine heart mitochondria.
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Applications:
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Immunoprecipitation
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Antigen Species Cross-Reactivity:
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human, bovine and mouse
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Storage:
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4°C
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Country of Origin:
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USA
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Product References
References for Complex II (Succinate ubiquinone oxidoreductase)
There are no references currently posted for this product.
Images
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