MS110 Complex I subunit NDUFS3
monoclonal antibody


$295.00 (100 µg)

Please contact us for volume discounts.
This product can also be ordered as part of a sample pack.


Brief Description & Uses

100 µg of monoclonal antibody reactive against the 30 kDa Complex I (NADH dehydrogenase) subunit NDUFS3. MS110 also labels NDUFS3 in immunocytochemical applications. This antibody is useful in studying Complex I assembly. Isolated mitochondria are available from several species for use as control samples. To see the complete list of control samples available from MitoSciences, click here.


Specifications

Product: Complex I subunit NDUFS3
monoclonal antibody
Catalog #: MS110
Lot #:
Clone ID: 3F9DD2
Host Species and Isotype: Mouse IgG1, κ
Immunogen: Whole mitochondria from Human Heart
Concentration: 1 mg/ml in Dulbecco’s Phosphate-Buffered Saline (PBS) with 0.02% azide as a preservative.
Purity: Near homogeneity as judged by SDS-PAGE. The antibodies were produced in vitro using hybridomas grown in serum-free medium, and then purified by biochemical fractionation.
Suggested Working Concentration: 0.5 µg/ml for Western blotting, 5-10 µg/ml for Immunocytochemistry
Applications: Western blotting, Immunocytochemistry
Antigen Species Cross-Reactivity: human, bovine, rat, mouse and Zebrafish
Storage: 4°C
Country of Origin: USA



Product References

J Clin Endocrin Metab. 2008 Jan 22; doi:10.1210/jc.2007-1701
"Activation of peroxisome proliferator activated receptor pathway stimulates the mitochondrial repiratory chain and can correct deficiencies in patients' cells lacking its components."

J Biol Chem. 2006 Sep 1;281(35):25398-406
"RNA silencing of mitochondrial m-Nfs1 reduces Fe-S enzyme activity both in mitochondria and cytosol of mammalian cells."

J Neurosci. 2006 May 10;26(19):5256-64.
"Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled."

Bio. Chem. Res. Comm. 2005;334(2):582-7.
"Fulminant neurological deterioration in a neonate with Leigh syndrome due to a maternally transmitted missense mutation in the mitochondrial ND3 gene."

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References for Complex I subunit NDUFS3

Mol Cell Proteomics. 2005 Jan;4(1):84-96
"Rapid purification and mass spectrometric characterization of mitochondrial NADH dehydrogenase (Complex I) from rodent brain and a dopaminergic neuronal cell line."



Images

NDUFS3 Western Blotting Image


NDUFS3 Immunocytochemistry Image


Downloadable Information
MS110 Specifications Western Blotting Protocol Immunocytochemistry Protocol


Additional Information
• Product Images
• Product References
• Protein References


Related Products
• Western Blotting Controls

• Secondary Antibodies

• MS851 Isolation Kit for Rodent Tissue
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