Thousands of researchers around the world are studying the connections between mitochondria, metabolism and disease. MitoNews summarizes a selection of the latest published findings and highlights how our MitoSciences range of research tools has contributed to this effort. Read the full list of 51 original research papers published this month.
Past issues are available for review in the archives.
This issue of MitoNews highlights Abcam's new ROS pathway card and identifies recent papers investigating different aspects of mitochondrial oxidative stress.
Download the pathway card: ROS impairs mitochondrial function
Related papers using MitoSciences products this month:
MITOCHONDRIAL RESPIRATORY SUPERCOMPLEX ASSOCIATION LIMITS PRODUCTION OF REACTIVE OXYGEN SPECIES FROM COMPLEX I Antioxid Redox Signal. 2013 Maranzana E, Barbero G, Falasca AI, Lenaz G, Genova ML.
Frataxin Deficiency Leads to Reduced Expression and Impaired Translocation of NF-E2-Related Factor (Nrf2) in Cultured Motor Neurons. Int J Mol Sci. 2013 D'Oria V, Petrini S, Travaglini L, Priori C, Piermarini E, Petrillo S, Carletti B, Bertini E, Piemonte F.
TOM40 mediates mitochondrial dysfunction induced by α-synuclein accumulation in Parkinson's disease. PLoS One. 2013. Bender A, Desplats P, Spencer B, Rockenstein E, Adame A, Elstner M, Laub C, Mueller S, Koob AO, Mante M, Pham E, Klopstock T, Masliah E.
Aconitase causes iron toxicity in Drosophila pink1 mutants. PLoS Genet. 2013. Esposito G, Vos M, Vilain S, Swerts J, De Sousa Valadas J, Van Meensel S, Schaap O, Verstreken P
Augmented Cardiac Formation of Oxidatively-Induced Carbonylated Proteins Accompanies the Increased Functional Severity of Post-Myocardial Infarction Heart Failure in the Setting of Type 1 Diabetes Mellitus. Cardiovasc Pathol. 2013. Dennis KE, Hill S, Rose KL, Sampson UK, Hill MF.
Roles of mitochondrial Src tyrosine kinase and zinc in nitric oxide-induced cardioprotection against ischemia/reperfusion injury. Free Radic Res. 2013. Zhang Y, Xing F, Zheng H, Xi J, Cui X, Xu Z.
Peroxisome Proliferator-Activated Receptor δ Agonist, HPP593, Prevents Renal Necrosis under Chronic Ischemia. PLoS One. 2013 Fedorova LV, Sodhi K, Gatto-Weis C, Puri N, Hinds TD Jr, Shapiro JI, Malhotra D.
Impaired mitochondrial function in chronically ischemic human heart. Am J Physiol Heart Circ Physiol. 2013. Stride N, Larsen S, Hey-Mogensen M, Hansen CN, Prats C, Steinbrüchel D, Køber L, Dela F
The TERE1 (UBIAD1) bladder tumor suppressor protein interacts with mitochondrial TBL2: regulation of trans-membrane potential, oxidative stress and SXR signaling to the nucleus. J Cell Biochem. 2013. Fredericks WJ, McGarvey T, Wang H, Zheng Y, Fredericks NJ, Yin H, Wang LP, Hsiao W, Lee R, Weiss JS, Nickerson ML, Kruth HS, Rauscher FJ 3rd, Malkowicz SB.
Nuclear localization of the mitochondrial factor HIGD1A during metabolic stress. PLoS One. 2013. Fredericks WJ, McGarvey T, Wang H, Zheng Y, Fredericks NJ, Yin H, Wang LP, Hsiao W, Lee R, Weiss JS, Nickerson ML, Kruth HS, Rauscher FJ 3rd, Malkowicz SB.
