Medium-chain acyl-CoA dehydrogenase (MCAD)

UniProt Number: P11310
Alternate Names: ACADM, medium-chain specific acyl-CoA dehydrogenase
Structure and Function: MCAD (medium-chain acyl-CoA dehydrogenase) is an oxidoreductase enzyme of the mitochondrial fatty acid beta-oxidation pathway that is specific for acyl chain lengths of 4 to 16. Utilizes the electron transfer flavoprotein (ETF) as electron acceptor that transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).
Disease Associations: Defects in ACADM are the cause of medium-chain acyl-CoA dehydrogenase deficiency (MCAD deficiency) [MIM:201450], an autosomal recessive disease which causes fasting hypoglycemia, hepatic dysfunction, and encephalopathy, often resulting in death in infancy.

Monoclonal Antibodies
Cat. No. Name Reactivity Apps. Amount
MS726 MCAD antibody human, bovine, rat, mouse WB, ICC, IHC, IP, ICE, FLOW 100 µg

Protein Quantity Assays
Cat. No. Name Reactivity Amount
ab129734 MCAD (ACADM) ELISA Kit Human 96 Tests

Multiplexing Arrays
Cat. No. Name Reactivity Amount
MSX32 MetaPath™ Fatty Acid Oxdiation 4-Plex Dipstick Array human 30 tests
90 tests

Flow Arrays
Cat. No. Name Reactivity Amount
MS978 MCAD, VLCAD, TFP - Fatty Acid Oxidation Human Flow Cytometry Kit human 96 tests

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Fatty Acid Oxidation (Mitochondrial)

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