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Caspase 9
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UniProt Number:
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P55211
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Alternate Names:
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Apoptotic protease Mch-6,Apoptotic protease-activating factor 3,Short name=APAF-3 ICE-like apoptotic
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Structure and Function:
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Caspase 9 is involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
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Disease Associations:
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n/a
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Monoclonal Antibodies
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Related Pathways:
Apoptosis
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