Enzymes > Carnitine palmitoyltransferase 2 (CPT2)
Carnitine palmitoyltransferase 2 (CPT2)
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UniProt Number:
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P23786
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Alternate Names:
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Carnitine O-palmitoyltransferase II, CPT II
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Structure and Function:
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Long chain fatty acids are shuttled into the mitochondrion for fatty acid oxidation via the carnitine shuttle. Carnitine is attached to long chain fatty acids at the mitochondrial outer membrane by the enzyme CPT1. These fatty acids are then released and reacted with CoA for oxidative breakdown by the inner membrane enzyme CPT2.
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Disease Associations:
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Defects in CPT2 are the cause of carnitine palmitoyltransferase 2 deficiency (CPT2D) [MIM:255110, MIM:600649] (also known as CPT-II deficiency or CPT2 deficiency) and carnitine palmitoyltransferase 2 deficiency, lethal neonatal (CPT2D-LN) [MIM:608836] (also known as lethal neonatal CPT-II deficiency).
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Monoclonal Antibodies
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Cat. No.
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Name
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Reactivity
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Apps.
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Amount
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Price
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MS722
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CPT2 antibody
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human, rat, mouse, bovine
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ICC, IP, ICE
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100 µg
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$325.00
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CART
