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Carnitine palmitoyltransferase 2 (CPT2)

UniProt Number: P23786
Alternate Names: Carnitine O-palmitoyltransferase II, CPT II
Structure and Function: Long chain fatty acids are shuttled into the mitochondrion for fatty acid oxidation via the carnitine shuttle. Carnitine is attached to long chain fatty acids at the mitochondrial outer membrane by the enzyme CPT1. These fatty acids are then released and reacted with CoA for oxidative breakdown by the inner membrane enzyme CPT2.
Disease Associations: Defects in CPT2 are the cause of carnitine palmitoyltransferase 2 deficiency (CPT2D) [MIM:255110, MIM:600649] (also known as CPT-II deficiency or CPT2 deficiency) and carnitine palmitoyltransferase 2 deficiency, lethal neonatal (CPT2D-LN) [MIM:608836] (also known as lethal neonatal CPT-II deficiency).

Monoclonal Antibodies
Cat. No. Name Reactivity Apps. Amount Price  
MS722 CPT2 antibody human, rat, mouse, bovine ICC, IP, ICE 100 µg $325.00

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Fatty Acid Oxidation (Mitochondrial)

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