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Bcl2 antagonist of cell death (Bad)

UniProt Number: Q92934
Alternate Names: Bcl-2-binding component 6, Bcl-2-like protein 8, Bcl-XL/Bcl-2-associated death promoter
Structure and Function: Bad promotes cell death. Bad successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Bad can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 By similarity. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Disease Associations: n/a

Protein Quantity Assays
Cat. No. Name Reactivity Amount
ab133984 Bad pSer75 Human ELISA Kit human, monkey 96 Tests

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