B-cell receptor-associated protein 31 (BCAP31)

UniProt Number: P51572
Alternate Names: 6C6-AG tumor-associated antigen, Protein CDM, p28
Structure and Function: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis.

Homodimer and heterodimer with BCAP29. Binds CASP8 (isoform 9) as a complex containing BCAP31, BCAP29, BCL2 and/or BCL2L1. Interacts with VAMP3, VAMP1 and membrane IgD immunoglobulins. May interact with ACTG1 and non-muscle myosin II. Interacts with PTPLB.
Disease Associations: Microdeletions in this gene are associated with the contiguous ABCD1/DXS1375E deletion syndrome (CADDS; MIM 300475). Northern blot analysis indicated higher expression of BCAP31 in breast cancer cells and pancreatic tissue compared with other tissues and cell lines.

Monoclonal Antibodies
Cat. No. Name Reactivity Apps. Amount
MS950 BCAP31 antibody human WB, IP, ICC, ICE, FLOW 100 µg

Protein Quantity Assays
Cat. No. Name Reactivity Amount
MS974 BAP31 Human ELISA Kit (ab116695) human 96 tests

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