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Monoamine oxidase A (MAOA)

UniProt Number: P21397
Alternate Names: amine oxidase [flavin-containing] A, monoamine oxidase A
Structure and Function: Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.
Disease Associations: Defects in MAOA are the cause of Brunner syndrome (BRUNS) [MIM:300615]. Brunner syndrome is a form of X-linked non-dysmorphic mild mental retardation.

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Xenobiotic Metabolism

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