All Research Kits
MS101
Complex I Immunocapture Kit
250 µg, 500 µg or 750 µg monoclonal antibody irreversibly crosslinked
to protein G-agarose beads which can immunocapture ~60 µg, ~120 µg or
~180 µg respectively of Complex I (NADH dehdydrogenase) from heart
mitochondria.
MS130
Dipstick Assay Kit for Complex I Activity
This
kit contains 30 or 60 dipsticks and necessary components for
quantitative analysis of NADH ubiquinone oxidoreductase activity in
human, bovine, rat, and mouse samples.
MS131
Dipstick Assay Kit for Human Complex I Quantity
This
kit contains 30 or 60 dipsticks and necessary components for
quantitative analysis of NADH ubiquinone oxidoreductase in human and
bovine samples.
MS133
Dipstick Assay Kit for Rodent Complex I Quantity
This
kit contains 30 or 60 dipsticks and necessary components for
quantitative analysis of NADH ubiquinone oxidoreductase in mouse and
rat samples.
MS141
Rapid Microplate Assay Kit for Complex I Activity
A rapid activity microplate kit that is used to determine the
activity of Complex I in a human sample with speed and simplicity.
Includes buffers, detergent, substrates, and 96-well microplate
with monoclonal antibody pre-bound to the wells of the plate,
allowing for a stream-lined assay.
MS142
Rapid Microplate Assay Kit for Complex I Quantity
A rapid activity microplate kit that is used to determine the
amount of Complex I in a human sample with speed and simplicity.
Includes buffers, detergent, substrates, and 96-well microplate
with monoclonal antibody pre-bound to the wells of the plate,
allowing for a stream-lined assay.
MS201
Complex II Immunocapture Kit
250
µg, 500 µg or 750 µg monoclonal antibodies irreversibly crosslinked to
protein G-agarose beads which can immunocapture ~13 µg, ~26 µg or ~39
µg respectively of Complex II from heart mitochondria.
MS202
Human Complex II Cocktail
Contains
a total of 300 µg or 600 µg of antibodies and is a pre-mixed solution
of 3 monoclonal antibodies against Complex II subunits 70 kDa Fp, 30
kDa Ip along with an antibody against Complex V α as a control. This
cocktail can be used to verify isolated Complex II purity or to
conveniently determine the levels of 2 of the 4 Complex II subunits in
patient cell lines relative to the control protein (Complex V α).
MS301
Complex III Immunocapture Kit
250 µg, 500 µg or 750 µg monoclonal antibodies irreversibly crosslinked
to protein G-agarose beads which can immunocapture ~25 µg, ~50 µg or
~75 µg respectively of Complex III from heart mitochondria.
MS401
Complex IV Immunocapture Kit
250
µg, 500 µg or 750 µg monoclonal antibodies irreversibly crosslinked to
protein G-agarose beads which can immunocapture ~25 µg, ~50 µg or ~75
µg respectively of Complex IV from heart mitochondria.
MS402
Complex IV Immunocapture Kit for Rodent
250
µg, 500 µg or 750 µg monoclonal antibodies irreversibly crosslinked to
protein G-agarose beads which can immunocapture ~25 µg, ~50 µg or ~75
µg respectively of Complex IV from heart mitochondria. The Complex IV
immunocapture kit allows isolation of the cytochrome c oxidase complex
(E.C. 1.9.3.1) from small amounts of rat or mouse tissue.
MS430
Dipstick Assay Kit for Human Complex IV Activity
This
kit contains 30 or 60 dipsticks and necessary components for
quantitative analysis of cytochrome c oxidase activity in human and
bovine samples.
MS431
Dipstick Assay Kit for Human Complex IV Quantity
This
kit contains 30 or 60 dipsticks and necessary components for
quantitative analysis of cytochrome c oxidase in human and bovine
samples.
MS432
Dipstick Assay Kit for Rodent Complex IV Activity
This
kit contains 30 or 60 dipsticks and necessary components for
quantitative analysis of cytochrome c oxidase activity in mouse and rat
samples.
MS441
Rapid Microplate Assay Kit for Human Complex IV Activity
A
rapid activity microplate kit that is used to determine the activity of
cytochrome c oxidase in a human sample with greater speed and
simplicity. Includes buffers, detergent, substrates, and 96-well
microplate with monoclonal antibody pre-bound to the wells of the
plate, allowing for a stream-lined assay.
MS442
Rapid Microplate Assay Kit for Human Complex IV Quantity
A rapid activity microplate kit that is used to determine the amount of
cytochrome c oxidase in a human sample with greater speed and
simplicity. Includes buffers, detergent, substrates, and 96-well
microplate with monoclonal antibody pre-bound to the wells of the
plate, allowing for a stream-lined assay.
MS443
Rapid Microplate Assay Kit for Human Complex IV Activity and Quantity
(Multiplexing)
A
96-well multiplexing microplate kit that is used to determine both the
activity and quantity of cytochrome c oxidase in a human sample with
greater speed and simplicity. Includes buffers, detergent, substrates,
and 96-well microplate with monoclonal antibody pre-bound to the wells
of the plate, allowing for a stream-lined assay.
MS444
Rapid Microplate Assay Kit for Mouse Complex IV Activity
A
96-well activity microplate kit that is used to determine the activity
of cytochrome c oxidase in a mouse sample with greater speed and
simplicity. Includes buffers, detergent, substrates, and 96-well
microplate with monoclonal antibody pre-bound to the wells of the
plate, allowing for a stream-lined assay.
MS445
Rapid Microplate Assay Kit for Mouse Complex IV Quantity
A
96-well activity microplate kit that is used to determine the amount of
cytochrome c oxidase in a mouse sample with greater speed and
simplicity. Includes buffers, detergent, substrates, and 96-well
microplate with monoclonal antibody pre-bound to the wells of the
plate, allowing for a stream-lined assay.
MS446
Rapid Microplate Assay Kit for Mouse Complex IV Activity and Quantity
(Multiplexing)
A
96-well multiplexing microplate kit that is used to determine both the
activity and quantity of cytochrome c oxidase in a mouse sample with
greater speed and simplicity. Includes buffers, detergent, substrates,
and 96-well microplate with monoclonal antibody pre-bound to the wells
of the plate, allowing for a stream-lined assay.
MS447
Rapid Microplate Assay Kit for Rat Complex IV Activity
A
96-well activity microplate kit that is used to determine the activity
of cytochrome c oxidase in a rat sample with greater speed and
simplicity. Includes buffers, detergent, substrates, and 96-well
microplate with monoclonal antibody pre-bound to the wells of the
plate, allowing for a stream-lined assay.
MS501 ATP
synthase (Complex V) Immunocapture Kit
250
µg, 500 µg or 750 µg of monoclonal antibodies irreversibly crosslinked
to protein G-agarose beads which can immunocapture ~125 µg, ~250 µg or
~500 µg respectively of ATP synthase (Complex V) from heart
mitochondria.
MS541
Rapid Microplate Assay Kit for ATP synthase (Complex V) Activity
A
rapid activity microplate kit that is used to determine the activity of
ATP synthase in human and rat samples with great speed and simplicity.
Includes buffers, detergent, lipid mix, substrates and 96-well
microplate with monoclonal antibody pre-bound to the wells of the
plate, allowing for a stream-lined assay.
MS542
Rapid Microplate Assay Kit for ATP synthase (Complex V) Quantity
A rapid activity microplate kit that is used to determine the amount of
ATP synthase in human and rat samples with great speed and simplicity.
Includes buffers, detergent, substrates, and 96-well microplate with
monoclonal antibody pre-bound to the wells of the plate, allowing for a
stream-lined assay.
MS543
Rapid Microplate Assay Kit for ATP synthase (Complex V) Activity and
Quantity (Multiplexing)
A
96-well multiplexing microplate kit that is used to determine both the
activity and quantity of ATP synthase in human and rat samples with
great speed and simplicity. Includes buffers, detergent, lipid mix,
substrates, and 96-well microplate with monoclonal antibody pre-bound
to the wells of the plate, allowing for a stream-lined assay.
MS601
MitoProfile® Human Total OXPHOS Complexes
Detection Kit
Contains
a total of 360 µg or 720 µg of antibodies and is a premixed solution of
5 monoclonal antibodies against a subunit of each of the 5 OXPHOS
complexes. Human heart mitochondria are also included as a Western
blotting control.
MS602
MitoProfile® OXPHOS/PDH Immunocytochemistry Kit
A
cocktail of 220 µg antibodies comprised of six mAbs packaged
individually. Each antibody is against a labile subunit of each of the
5 OXPHOS complexes and PDH. Each mAb is provided in a 50 µl aliquot at
a 200x concentration, to allow reconstitution of each mAb in 10 ml
working volume.
MS602a
MitoProfile® OXPHOS/PDH Immunocytochemistry Kit
Includes
the same components as MS602 (above), but additionally contains 60 µg
mAb to porin, and 120 µg to Complex V α subunit, and the required
secondary antibodies for simultaneous 2 dye staining of samples.
MS603
MitoProfile® Total OXPHOS Complexes Blue Native
Blotting Detection Kit
A
cocktail of mAbs which allows the rapid and highly sensitive detection
of OXPHOS components from very small sample amounts. This cocktail
allows the simultaneous analysis of the assembly state of all 5 OXPHOS
complexes from a single patient sample. Bovine heart mitochondria are
also included as a control sample.
MS604
MitoProfile® Rodent Total OXPHOS Complexes
Detection Kit
Contains
a total of 300 µg or 600 µg of antibodies and is a premixed solution of
5 monoclonal antibodies against a subunit of each of the 5 OXPHOS
complexes in mitochondrial preparations from rodent sources. Mouse
brain mitochondria are also included as a Western blotting control.
MS620
MitoProfile® Mitochondria Membrane Integrity Kit
Contains 255 µg of 5 mAbs against representative proteins for each of
the primary structures of the mitochondrion: the outer membrane, the
intermembrane space, the inner membrane, and the matrix space. This kit
is useful in Western blotting to evaluate the structural integrity of
isolated mitochondria. Human Heart Mitochondria are provided as
standard control, mitochondria from other species and tissue available.
MS631
MitoProfile® Biogenesis Dipstick Assay Kit
MS631 is a rapid and simple test for determining whether mitochondrial
biogenesis has been up-regulated or down-regulated in human samples.
The assay works on very small amounts of sample material, including
cheek swabs or single drops of blood, and results can be generated in
under 30 minutes.
MS641
MitoProfile® Biogenesis Microplate Assay Kit
MS641 is a high-throughput test for determining whether mitochondrial
biogenesis has been up-regulated or down-regulated in human samples.
The assay works on very small amounts of sample material and is suitable
for screening of antiviral and antibiotic drugs.
MS740
Rapid Microplate Assay Kit for Human Mitochondrial Trifunctional
Protein (MTP)
This kit is used to determine the assembled enzyme quantity of
Mitochondrial Trifunctional Protein (MTP) in a human sample with speed
and simplicity.
MS741
Dipstick Assay Kit for Human Mitochondrial Trifunctional Protein (MTP)
Contains
30 or 60 dipsticks and necessary components to quantify the amount of
the Mitochondrial Trifunctional Protein (MTP) from human sample
material.
MSA01 ANT
Immunocapture Kit
250 µg
monoclonal antibody irreversibly crosslinked to protein G-agarose beads
which can immunocapture ANT from heart mitochondria.
MSA07
ApoTrack™ Apoptosis Detection Kit for Immunocytochemistry
MSA07 detects apoptotic cells with high specificity. It contains an
anti-cytochrome c monoclonal antibody (50 µg) and the appropriate
isotype-specific secondary antibody (50 µg) which has a fluorescein
fluorophore conjugated to it. The kit also contains an anti-Complex Vα
monoclonal antibody (50 µg) and the appropriate Texas Red
fluorophore-conjugated isotype-specific secondary antibody (50 µg).
Complex V serves as a mitochondrial marker in healthy and apoptotic
cells.
MSA11 ApoTrack™ Cytochrome c Apoptosis Kit
Contains
180 µg of premixed cocktail of 4 monoclonal antibodies and necessary
buffers and detergent allowing for a rapid method to measure the
fraction of cytochrome c
released from mitochondria into the cytosol during apoptosis. Human
heart mitochondria are included as a Western blotting control.
MSA12 ApoTrack™ Apoptosis Detection Kit for Western blotting
Contains 180 µg of premixed cocktail of 4 monoclonal antibodies that
allows detection of cytochrome c
in the cytoplasmic and mitochondria-containing fractions by Western
Blot analysis to determine the proportion of released cytochrome c
from mitochondria to cytoplasm. Human heart mitochondria are also
included as a Western blotting control.
MSA31
Dipstick Assay Kit for Apoptosis-Inducing Factor (AIF) Quantity
This kit contains 30 or 60 dipsticks and necessary components to
quantify the amount of Apoptosis-Inducing Factor (AIF) from human
sample material.
MSA41
Rapid Microplate Assay Kit for Cytochrome c Quantity
A 96-well activity microplate kit that is used to determine the amount
of cytochrome c
in a human, bovine, mouse, or rat samples. Includes detergent,
substrates, and 96-well microplate with monoclonal antibody pre-bound
to the wells of the plate, allowing for a stream-lined assay.
MSA42
Rapid Microplate Assay Kit for Apoptosis-Inducing Factor (AIF)
AIF is a flavoprotein (67 kDa) localized in the inter-membrane space.
It is a multi-functional protein with a vital oxidoreductase function
(required for cell survival), an anti-oxidant activity, an assembly
function in Complex I (NADH-ubiquinone oxidoreductase complex)
formation and an apoptogenic function. AIF has a major role in the
caspase-independent apoptosis process. It translocates to the nucleus
after mitochondrial release, leading to chromatin condensation and DNA
fragmentation.
MSF31
Dipstick Assay Kit for Frataxin
This kit contains 30 or 60 dipsticks and necessary components for
quantitative analysis of human frataxin protein levels.
MSF41
Rapid Microplate Assay Kit for Frataxin
Frataxin is a nuclear-encoded mitochondrial protein. In humans the gene
is localized on chromosome 9 and is highly conserved during evolution.
The gene is expressed in every cell, although in varying levels in
different tissues and during development. Friedreich's Ataxia (FRDA) is
an inherited recessive neurodegenerative disorder caused by decreased
expression levels of frataxin. FRDA is the most common inherited ataxia
and it causes progressive damage to the nervous system, resulting in
symptoms ranging from muscle weakness and speech problems to heart
disease. About one in 50,000 people in the United States have
Friedreich's Ataxia.
MSP01 PDH
Immunocapture Kit
250 µg
monoclonal antibody irreversibly crosslinked to protein G-agarose beads
which can immunocapture ~13 µg of PDH complex from heart mitochondria.
MSP02
MitoProfile™ PDH Subunit Western Blotting Kit
Contains a total of 150 µg or 300 µg respectively of monoclonal
antibodies reactive against PDH subunits.
MSP18
Rapid Microplate Assay Kit for PDH Activity
A
rapid activity microplate kit that is used to determine the activity of
PDH in a human, bovine, mouse, or rat sample with greater speed and
simplicity. Includes buffer, detergent, reagent mix, and 96-well
microplate with monoclonal antibody pre-bound to the wells of the
plate, allowing for a stream-lined assay.
MSP19
Rapid Microplate Assay Kit for PDH Quantity
A 96-well activity microplate kit that is used to determine the amount
of PDH in a human, bovine, mouse, or rat sample. Includes buffers,
detergent, substrates, and 96-well microplate with monoclonal antibody
pre-bound to the wells of the plate, allowing for a stream-lined assay.
MSP20
Rapid Mitcroplate Assay Kit for PDH Activity (Combo)
A
combination of MSP18 and MSP19 microplate assay kits that are used to
determine both the activity and quantity of PDH in a human, bovine,
mouse, or rat sample. Includes buffers, detergent, reagent mix,
substrates, and 96-well microplate with monoclonal antibody pre-bound
to the wells of the plate, allowing for a stream-lined assay.
MSP30
Dipstick Assay Kit for PDH Activity
This kit contains 30 or 60 dipsticks and necessary components for
quantitative analysis of PDH activity in human, bovine, mouse, rat, and
pig samples.
MSP31
Dipstick Assay Kit for PDH Quantity
This
kit contains 30 or 60 dipsticks and necessary components for
quantitative analysis of PDH in human, bovine, mouse, and rat samples.
MS850
Mitochondria Isolation Kit for Rodent Tissue
Contains
sufficient reagents for up to 10 benchtop mitochondria isolations from
hard or soft rodent tissues. Isolated mitochondria can be analyzed by
Western Blotting, Immunocapture, or Activity assay.
MS851
Mitochondria Isolation Kit for Rodent Tissue (with Dounce Homogenizer)
Contains
sufficient reagents and a homogenizer for up to 10 benchtop
mitochondria isolations from hard or soft rodent tissues. Isolated
mitochondria can be analyzed by Western Blotting, Immunocapture, or
Activity assay.
MS852
Mitochondria Isolation Kit for Cultured Cells
Contains
sufficient reagents for up to 20 benchtop mitochondria isolations from
human cultured cells. Isolated mitochondria can be analyzed by Western
Blotting, Immunocapture, or Activity assay.
MS853
Mitochondria Isolation Kit for Cultured Cells (with Dounce Homogenizer)
Contains
sufficient reagents and a homogenizer for up to 20 benchtop
mitochondria isolations from human cultured cells. Isolated
mitochondria can be analyzed by Western Blotting, Immunocapture, or
Activity assay.
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