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Acetyl-CoA acyltransferase 2 (ACAA2)

UniProt Number: P42765
Alternate Names: 3-ketoacyl-CoA thiolase, beta-ketothiolase, mitochondrial 3-oxoacyl-CoA thiolase, 3,Aioxoacyl-CoA thiolase, T1
Structure and Function: Acetyl-CoA acyltransferase 2 (ACAA2), also called 3,Aioxoacyl-CoA thiolase, is a mitochondrial enzyme catalyzing the last step in fatty acid oxidation to release acetyl CoA for Krebs cycle activity. Recent studies suggest an involvement of this enzyme in apoptosis as a functional partner of the pro-apoptotic protein BNIP3. Apoptosis induced by overexpression of BNIP3 was abolished by ACAA2.
Disease Associations: n/a

Protein Quantity Assays
Cat. No. Name Reactivity Amount Price  
MSFX-21 ACAA2 FlexPlex™ Module human 4 strips (32 tests) $125.00

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Acetyl-CoA Metabolism: Key Nodes

Fatty Acid Oxidation (Mitochondrial)

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