Enzymes > Acetyl-CoA acyltransferase 2 (ACAA2)
Acetyl-CoA acyltransferase 2 (ACAA2)
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UniProt Number:
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P42765
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Alternate Names:
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3-ketoacyl-CoA thiolase, beta-ketothiolase, mitochondrial 3-oxoacyl-CoA thiolase, 3,Aioxoacyl-CoA thiolase, T1
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Structure and Function:
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Acetyl-CoA acyltransferase 2 (ACAA2), also called 3,Aioxoacyl-CoA thiolase, is a mitochondrial enzyme catalyzing the last step in fatty acid oxidation to release acetyl CoA for Krebs cycle activity. Recent studies suggest an involvement of this enzyme in apoptosis as a functional partner of the pro-apoptotic protein BNIP3. Apoptosis induced by overexpression of BNIP3 was abolished by ACAA2.
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Disease Associations:
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n/a
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Protein Quantity Assays
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CART
