UniProt Number: | P00560 |
Alternate Names: | PEP1, Carboxypeptidase Y receptor Short name=CPY receptor Carboxypeptidase Y-deficient protein 1 Sortilin VPS10 Vacuolar carboxypeptidase sorting receptor VPS10 Vacuolar protein sorting-associated protein 10 Vacuolar protein-targeting protein 1 |
Structure and Function: | Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. May execute multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment. Binds the Golgi-modified P2 form of CPY, and this interaction is dependent on the presence of an intact CPY vacuolar protein sorting signal. |
Disease Associations: |