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V-type proton ATPase subunit B

UniProt Number: P16140
Alternate Names: V-ATPase 57 kDa subunit
Vacuolar proton pump subunit B, VMA2
Structure and Function: Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. It is an electrogenic proton pump that generates a proton motive force of 180 mv, inside positive and acidic, in the vacuolar membrane vesicles.V-ATPase is an heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d and e). Interacts with RAV1 and RAV2 components of the RAVE complex, which are essential for the stability and assembly of V-ATPase.
Disease Associations:  

Monoclonal Antibodies
Cat. No. Name Reactivity Apps. Amount
MSZ03 VMA2 antibody Yeast ICC, WB 250 µg

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