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SRA stem-loop-interacting RNA-binding protein, mitochondrial

UniProt Number: Q9GZT3
Alternate Names: SLIRP, C14orf156
Structure and Function: SLIRP is a RNA binding protein that acts as a nuclear receptor corepressor. It may act by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. SLIRP binds the STR7 loop of SRA RNA. It is also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation. It contains 1 RRM (RNA recognition motif) domain. SLIRP is predominantly founs in mitochondrial with a limited role in the nucleus where it is recruited to nuclear receptor target promoters.
Disease Associations: n/a

Monoclonal Antibodies
Cat. No. Name Reactivity Apps. Amount
ab119687 SLIRP Antibody Human WB, ICC, IHC, ICE, FLOW 100 µg

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