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Nucleolin (NCL)

UniProt Number: P19338
Alternate Names: Nucleolin, NCL
Structure and Function: Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.
Disease Associations: NA

Monoclonal Antibodies
Cat. No. Name Reactivity Apps. Amount
ab136649 Nucleolin antibody human WB, IP, Flow Cyt, In-Cell ELISA, ICC 100 µg
ab154028 Anti-Nucleolin antibody(Alexa FluorŪ 488) human Flow Cyt, ICC 100 µg

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