B-cell lymphoma/leukemia 11B protein (CTIP1/BCL11A)

UniProt Number: Q9H165
Alternate Names: COUP-TF-interacting protein 1, CTIP1, CTIP1, EVI9, KIAA1809, ZNF856
Structure and Function: Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. An essential factor in lymphopoiesis, is required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1.Expressed at high levels in brain, spleen thymus, bone marrow and testis. Expressed in CD34-positive myeloid precursor cells, B-cells, monocytes and megakaryocytes. Expression is tightly regulated during B-cell development.
Disease Associations:  Chromosomal aberrations involving BCL11A may be a cause of lymphoid malignancies.

Protein Quantity Assays
Cat. No. Name Reactivity Amount
ab126586 CTIP1 ELISA human 96 Tests  

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