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Citrate Synthase (CS)
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UniProt Number:
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O75390
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Alternate Names:
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CS
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Structure and Function:
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Citrate synthase (CS, O75390) is the initial enzyme of the tricarboxylic acid (TCA) cycle. This enzyme is a 51.7 kDa enzyme that catalyzes the reaction of 2 carbon acetyl CoA with 4 carbon oxaloacetate to form the 6 carbon citrate (EC 2.3.3.1). This enzyme is an exclusive marker of the mitochondrial matrix. Citrate synthase is found in nearly all cells capable of oxidative metabolism.
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Disease Associations:
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n/a
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Activity Assays
Specific Activity Assays
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