Proteins > Very long-chain acyl-CoA dehydrogenase (VLCAD)
Very long-chain acyl-CoA dehydrogenase (VLCAD)
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UniProt Number:
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P49748
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Alternate Names:
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Very long-chain specific acyl-CoA dehydrogenase, ACADVL
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Structure and Function:
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A mitochondrial inner membrane enzyme, VLCAD is active toward esters of long-chain and very long-chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accomodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons.
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Disease Associations:
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Defects in ACADVL are the cause of very long chain acyl-CoA dehydrogenase deficiency (VLCAD deficiency) [MIM:201475]. VLCAD deficiency is an autosomal recessive disease which leads to impaired long-chain fatty acid beta-oxidation.
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Monoclonal Antibodies
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Cat. No.
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Name
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Reactivity
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Apps.
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Amount
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Price
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MS707
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VLCAD Antibody
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Human, Mouse, Rat, Bovine
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ICC, IHC, IP
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100 µg
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$325.00
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