MitoProfile® Pyruvate dehydrogenase (PDH) WB Antibody Cocktail

Catalog No. MSP02

$395.00 - 150 µg
$695.00 - 300 µg


Product Description

Contains a total of 150 µg or 300 µg respectively of monoclonal antibodies reactive against PDH subunits. Isolated mitochondria are available from several species for use as control samples. To see the complete list of control samples available from MitoSciences, click here.

The PDH Western blotting kit contains four different mAbs reacting specifically with E1 alpha, E1 beta, E2 and E2/E3bp. A mAb against the OSCP subunit of ATP synthase is included as a control. This mAb mixture can be used to probe the isolated pyruvate dehydrogenase for integrity and purity as shown in the figure at left. Also included in this kit are SDS-dissociated human heart mitochondria to use as a control for the identification of PDH subunits on the gel system chosen for analysis.



 
Data
 
Documentation
 
Citations

Product Specifications
 
Targets: • PDH subunit E1 alpha ~ 42kD
• PDH subunit E1 beta ~ 35kD
• PDH subunit E2 ~ 72kD
• PDH subunit E2/E3bp ~ 55kD
• ATP synthase subunit OSCP ~ 20kD
Species Reactivity: human, bovine
Storage Conditions: 4°C
Country of Origin: USA


Top



Specifications
 
 
Documentation
 
Citations
Figure 1





Top



Specifications
 
Data
 
 
Citations

Downloadable Documents


   Technical Data Sheet

   Protocol

   PDH Playbook


Top



Specifications
 
Data
 
Documentation
 

Published Studies Using This Product: Quintana et al., 2009. PDH E(1)beta deficiency with novel mutations in two patients with Leigh syndrome.

Bonnet et al., 2007. A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth.

Richards et al., 2006. Postischemic hyperoxia reduces hippocampal pyruvate dehydrogenase activity.


Have you published studies using this product?
Let us know by filling out this form and receive a $100 discount on your next order.


Top



Browse Products By:
Search:



Sales & Customer Support:
1-800-910-6486

sales@mitosciences.com

Copyright © 2010 MitoSciences Inc. All rights reserved.