MSA08 Porin monoclonal antibody
for yeast


$295.00 (100 g)

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This product can also be ordered as part of a sample pack.



Brief Description & Uses

100 g of monoclonal antibody reactive against porin for use in Western blotting applications.

The channel-forming protein porin (also called the voltage dependent anion channel, VDAC) is involved in both aerobic metabolism and apoptotic processes. Porin is localized in the outer membrane of mitochondria where it forms the primary pathway of metabolites across the membrane. Porin can also serve as a binding site for enzymes or a regulatory molecule.

Multiple isoforms of porin have been identified in mammals and plants. In Saccharomyces cerevisiae one isoform showing properties that are conserved among other species has been identified (POR1). The second gene (POR2) discovered does not exhibit the channel forming activity. However, yeast strains in which the POR1 gene has been deleted (Dpor1) can still grow on yeast media containing a nonfermentable carbon source. Thus, the second protein present can partially substitute for that function in a non-channel dependent way.


Specifications

Product: Porin monoclonal antibody
for yeast
Catalog #: MSA08
Lot #:
Clone ID: 16G9E6BC4
Host Species and Isotype: Mouse IgG1, κ
Immunogen: VDAC-1 from S. cerevisiae, denatured in SDS-PAGE
Concentration: 1 mg/ml in Hepes-Buffered Saline (HBS) with 0.02% azide as a preservative.
Purity: Near homogeneity as judged by SDS-PAGE. The antibodies were produced in vitro using hybridomas grown in serum-free medium, and then purified by biochemical fractionation.
Suggested Working Concentration: 0.1 g/ml for Western blotting
Applications: Western blotting
Antigen Species Cross-Reactivity: S. cerevisiae
Storage: 4C
Country of Origin: USA



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References for Porin

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Images



Downloadable Information
MSA08 Specifications Western Blotting Protocol


Additional Information
Product Images
Product References
Protein References


Related Products
Western Blotting Controls

Secondary Antibodies
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