MS420 Complex IV subunit IV (Cox4p)
monoclonal antibody for yeast


$295.00 (100 g)

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This product can also be ordered as part of a sample pack.



Brief Description & Uses

100 g of monoclonal antibody reactive against Complex IV subunit IV for use in Western blotting.

In yeast Saccharomyces cerevisiae, cytochrome c oxidase (COX) is composed of 11 subunits, three of which are encoded in the mitochondrial genome (Cox1p, Cox2p and Cox3p). These three large subunits are transmembrane proteins that form the catalytic core of the enzyme.

The remaining subunits (Cox4p-Cox9p) are nuclear encoded and transported into the mitochondria after translation. Although the specific functions of the subunits are not completely understood, they are known to be involved in the assembly of the enzyme. Studies with yeast strains carrying null mutations in these subunits have shown complete loss of COX activity, suggesting that the subunits play a crucial role in assembly and stability of the enzyme. The COX assembly process is conserved between human and yeast.


Specifications

Product: Complex IV subunit IV (Cox4p)
monoclonal antibody for yeast
Catalog #: MS420
Lot #:
Clone ID: 1A12A12
Host Species and Isotype: Mouse IgG1, κ
Immunogen: Native Complex IV from S. cerevisiae
Concentration: 1 mg/ml in HEPES-Buffered Saline (HBS) with 0.02% azide as a preservative.
Purity: Near homogeneity as judged by SDS-PAGE. The antibodies were produced in vitro using hybridomas grown in serum-free medium, and then purified by biochemical fractionation.
Suggested Working Concentration: 1.0 g/ml for Western blotting
Applications: Western blotting
Antigen Species Cross-Reactivity: S. cerevisiae
Storage: 4C
Country of Origin: USA



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Images



Downloadable Information
MS420 Specifications Western Blotting Protocol Research Playbook


Additional Information
Product Images
Product References
Protein References


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Secondary Antibodies
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