MetaPath™ Multiplex Microplate Arrays
MetaPath™ arrays are built on the well-established sandwich ELISA concept, whereby capture and detector antibodies are used to first immobilize and then quantitate a protein/enzyme target. Multiplex arrays extend this concept to very high-throughput by spotting the capture antibodies in arrays on the bottom of 96-well plates. Detector antibodies with enzyme-linked tags are then added in one solution, and the relative amount of each target is read by an imager.
MetaPath™ arrays have been rigorously tested to remove cross-talk between detector antibodies, and have been developed for compatible working ranges for each target in the array. These assays are ideal for drug screening applications where multiple targets in a pathway need to be measured simultaneously.
MetaPath™ arrays utilize our proprietary EnzymeLok™ immunocapture antibodies, which are able to capture large enzyme complexes in their fully-intact and functionally-active states.
MetaPath™ Microplate Arrays