Proteins > Medium-chain acyl-CoA dehydrogenase (MCAD)
Medium-chain acyl-CoA dehydrogenase (MCAD)
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UniProt Number:
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P11310
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Alternate Names:
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ACADM, medium-chain specific acyl-CoA dehydrogenase
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Structure and Function:
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MCAD (medium-chain acyl-CoA dehydrogenase) is an oxidoreductase enzyme of the mitochondrial fatty acid beta-oxidation pathway that is specific for acyl chain lengths of 4 to 16. Utilizes the electron transfer flavoprotein (ETF) as electron acceptor that transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).
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Disease Associations:
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Defects in ACADM are the cause of medium-chain acyl-CoA dehydrogenase deficiency (MCAD deficiency) [MIM:201450], an autosomal recessive disease which causes fasting hypoglycemia, hepatic dysfunction, and encephalopathy, often resulting in death in infancy.
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Monoclonal Antibodies
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Cat. No.
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Name
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Reactivity
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Apps.
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Amount
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Price
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MS726
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MCAD antibody
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human, bovine, rat, mouse
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WB, ICC, IHC, IP
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100 µg
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$325.00
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Protein Quantity Assays
Multiplexing Arrays
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CART
