Proteins > Dicarbonyl/L-xylulose reductase (DCXR)
Dicarbonyl/L-xylulose reductase (DCXR)
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UniProt Number:
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Q7Z4W1
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Alternate Names:
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XR, l-xylulose reductase, kidney dicarbonyl reductase, carbonyl reductase II, sperm surface protein P34H, kiDCR
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Structure and Function:
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DCXR is an oxidoreductase enzyme that catalyzes the NADPH-dependent reduction of several pentoses, tetroses, alpha-dicarbonyl compounds and L-xylulose. DCXR is part of the uronate cycle in glucose metabolism and is highly expressed in kidney and liver. Weak expression or not expressed in brain and heart tissue.
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Disease Associations:
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Defects in DCXR are a cause of pentosuria [MIM: 260800]; also known as L-xylulosuria or xylitol dehydrogenase deficiency. Pentosuria is an inborn error of carbohydrate metabolism, characterized by the excessive urinary excretion of the sugar xylitol.
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Monoclonal Antibodies
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Cat. No. |
Name |
Reactivity |
Apps. |
Amount |
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MS704 |
DCXR antibody |
human |
WB, ICC, IP, ICE, FLOW |
100 µg |
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