Frataxin monoclonal antibody

Catalog No. MSF01

$325.00 - 100 µg


This antibody can also be purchased as part of a Sample Pack.


 
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Citations

Product Specifications
 
Applications: Western blotting and Immunocytochemistry
Species Reactivity: human
Host Species: mouse
Isotype: IgG1, k
Clone ID: 18A5DB1
Concentration: 1.0 mg/mL in Hepes-Buffered Saline (HBS) with 0.02% azide as a preservative.
Suggested Working Concentration: 3-5 µg/mL for Western blotting (a chemiluminescent detection system is highly recommended), 0.5 µg/mL for Immunocytochemistry
Storage Conditions: 4°C
Country of Origin: USA


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WB Images



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Figure 1. Recombinant Human Frataxin (lane 1) detected with (MSF01) anti-Frataxin antibody.
ICC Images



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Figure 2. Mitochondrial localization of Frataxin in normal human fibroblasts visualized by immunocytochemistry using anti-frataxin mAb 18A5DB1 (MSF01). Cultured human embryonic lung-derived fibroblasts (strain MRC5) were fixed, permeabilized and then labeled with MSF01 (0.5 µg/ml) followed by an AlexaFluor® 594-conjugated-goat-anti-mouse IgG1 isotype specific secondary antibody (2 µg/ml).


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Specifications
 
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Citations

Downloadable Documents


   Technical Data Sheet

   Western blotting Protocol

   Immunocapture Protocol


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Specifications
 
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Documentation
 

Published Studies Using This Product: Nadanaciva et al., 2009. Lateral-flow immunoassay for detecting drug-induced inhibition of mitochondrial DNA replication and mtDNA-encoded protein synthesis.

Chou et al., 2008. Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I histone deacetylases.

Schmucker et al., 2008. The in vivo mitochondrial two-step maturation of human frataxin.

Long et al., 2008. Mitochondrial localization of human frataxin is necessary but processing is not for rescuing frataxin deficiency in Trypanosoma brucei.

Willis et al., 2008. Lateral-flow immunoassay for the frataxin protein in Friedreich's ataxia patients and carriers.

Li et al., 2008. Iron-dependent regulation of frataxin expression: implications for treatment of Friedreich ataxia.


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