Complex I subunit NDUFB6 monoclonal antibody
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Catalog No. MS108
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$325.00 - 100 µg
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UniProt Number:
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O95139
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Alternate Names:
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NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6, NADH-ubiquinone oxidoreductase B17 subunit, Complex I-B17, CI-B17, NDUFB6
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Structure and Function:
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There are 45 unique subunits of Complex I, and this subunit is 128 AA long. It is thought that this subunit does not contribute to catalytic functions of Complex I.
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Product Specifications
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Applications:
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Western blotting
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Species Reactivity:
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human, mouse, rat, bovine
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Host Species:
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mouse
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Isotype:
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IgG2b, κ
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Clone ID:
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21C11BC11
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Concentration:
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1 mg/mL in Hepes-Buffered Saline (HBS) with 0.02% azide as a preservative.
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Suggested Working Concentration:
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0.5 µg/mL for Western blotting
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Storage Conditions:
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Store at 4°C. Do not freeze.
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Country of Origin:
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USA
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WB Images
(click to enlarge)
Figure 1. Isolated mitochondria from human heart (lane 1), bovine heart (lane 2), rat heart (lane 3), and mouse heart (lane 4) detected with (MS108) anti-NDUFB6 antibody.
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Published Studies Using This Product:
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Fassone et al., 2010. FOXRED1, encoding a FAD-dependent oxidoreductase complex-I specific molecular chaperone, is mutated in infantile-onset mitochondrial encephalopathy.
Folbergrová et al., 2009. Sustained deficiency of mitochondrial complex I activity during long periods of survival after seizures induced in immature rats by homocysteic acid.
Janssen et al., 2009. Contiguous gene deletion of ELOVL7, ERCC8 and NDUFAF2 in a patient with a fatal multisystem disorder.
Rardin et al., 2009. Monitoring phosphorylation of the pyruvate dehydrogenase complex.
Potluri et al., 2009. A novel NDUFA1 mutation leads to a progressive mitochondrial complex I-specific neurodegenerative disease.
Rardin et al., 2008. Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane.
Ling et al., 2007. Genetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscle.
Vogel et al., 2007. Identification of mitochondrial complex I assembly intermediates by tracing tagged NDUFS3 demonstrates the entry point of mitochondrial subunits.
Lee et al., 2006. Changes in gene expression with increased transglutaminase 2 in a SH-SY5Y cell line.
Schilling et al., 2005. Rapid purification and mass spectrometric characterization of mitochondrial NADH dehydrogenase (Complex I) from rodent brain and a dopaminergic neuronal cell line.
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CART
