Advancing vital discoveries in mitochondrial research.

 

About Us
MitoScience LLC was founded in July 2003 by Professor Roderick A. Capaldi and Dr. Michael F. Marusich of the University of Oregon to leverage their extensive backgrounds in the study of the mitochondria, mitochondrial-related diseases and the development of mitochondrial specific monoclonal antibodies especially those that capture individual complexes of the mitochondria with preserved function and activity.

Rod A. Capaldi, D. Phil., Co-founder - Dr. Capaldi was educated at London University (BSc) and York University (DPhil).  He is Knight Professor of the Arts and Sciences and member of the prestigious Institute of Molecular Biology at the University of Oregon.  Publisher of more than 200 papers in the area of mitochondrial function and disease, Dr. Capaldi has been Established Investigator of the American Heart Association and recipient of the Medical Research Foundation of Oregon Medal.

Michael F. Marusich, Ph.D., Co-founder – Dr. Marusich received his BS in Zoology from the University of Michigan in 1975 and MS and PhD degrees in Biology from Northwestern University in 1976 and 1981 respectively.  Becoming associated with the Department of Biology of the University of Oregon in 1981, he has served as a Research Associate and Professor.  Since 1986 Dr. Marusich has served as the Director of the Monoclonal Antibody Facility of the University of Oregon.  Dr. Marusich has published more than 30 papers on the development of novel immunoassays and techniques and on immunochemical-based research of early development and mitochondrial disorders.

Richard E. Sloan, Business Director - Mr. Sloan has most recently been involved in the start-up of a pharmaceutical software business for Incova Group Inc. after relocating to the Eugene area at the end of 2002.  Prior to this he was VP of Operations and Business Development for Miracor Diagnostics, Inc., a publicly traded multi-site diagnostic imaging company.  Throughout his career, he has held various executive positions with start-up and turn-around medical device and service companies with direct responsibility for product development, business development, mergers and acquisitions, licensing, marketing and general management.  Earlier in his career, Mr. Sloan was a marketing manager with the IVAC division of Eli Lilly following his tenure as an international product marketing manager with Baxter.  Mr. Sloan began his career with the MicroSwitch division of Honeywell as a manufacturing process design engineer for high-volume automated thin and thick-film solid-state device fabrication.  He studied Biochemistry and Chemical Engineering at the University of Illinois where he received a BS and completed his MBA in finance from the University of Chicago.

Lynnor B. Stevenson Ph.D., Member Business Advisory Committee –   Ms. Stevenson is Managing Partner and Cofounder, Alta Biomedical Group, Oregon, a consulting firm focusing on commercialization of life science technology with research institutions, small companies and investors. Dr. Stevenson has over twenty-five years experience in bioscience ventures based on university research and has been an officer, founder and/or director of more than ten start-up biotechnology companies. Five of these companies are now public, another three were acquired. She was the founding President and remains a Director of Heska Corporation, a public company that provides innovative products for the diagnosis, treatment and prevention of disease in companion animals.

Robert Aggeler, Dr. sc. nat. ETH Senior Scientist –  Dr. Aggeler received an MS and a PhD at the Institute of Biochemistry of the Swiss Federal Institute of Technology (ETH) in 1980 and 1984 respectively. After a one year stay as post-doctoral research scientist in Hoffmann-LaRoche, Basel, he has worked as a research associate at the University of Oregon in the Institute of Molecular Biology. His studies on E. coli ATP synthase and on complexes involved in oxidative phosphorylation of yeast and mammalian mitochondria are published in more than 40 papers.

James G. Murray, Ph.D., Senior Scientist –  Dr. Murray graduated from the University of Edinburgh, UK, in 1994 with a B.Sc. honors degree in Biochemistry. In 1998 he was awarded a PhD from the University of Leeds, UK, for studies upon the structure/function of the yeast vacuolar type ATPase under the supervision of Prof. J. B. C. Findlay. He has since then served as a post-doctoral research associate in the Institute of Molecular Biology at the University of Oregon where he has studied the organization of the multi-subunit enzymes of oxidative phosphorylation as well as developing novel methods to generate and characterize antibodies for the isolation of these complexes.

Sashi Nadanaciva, DPhil, Senior Scientist. –   Dr. Nadanaciva was educated at the University of Oxford, UK, where she received a DPhil, in 1995, for studies on the ATP synthase, and a BA in Biochemistry prior to that. She continued to work in the field of bioenergetics during four years of postdoctoral research at the University of Rochester, NY. She is an author on more than 10 papers on the ATP synthase. Before joining Mitosciences, she was at Pharmacia Corporation in Illinois where she worked on identifying and measuring peptide biomarkers using HPLC-linked to immunoassays.