Publications referencing MitoSciences Products - MitoNews January 2015

Estrogen regulates energy metabolic pathway and upstream adenosine 5'-monophosphate-activated protein kinase and phosphatase enzyme expression in dorsal vagal complex metabolosensory neurons during glucostasis and hypoglycemia.
Tamrakar P, Ibrahim BA, Gujar AD, Briski KP.


Differential proteomic profiling unveils new molecular mechanisms associated with mitochondrial complex III deficiency.
Marin-Buera L, Garcia-Bartolome A, Moran M, Lopez-Bernardo E, Cadenas S2, Hidalgo B, Sanchez R, Seneca S, Arenas J, Martin MA, Ugalde C.


Riboflavin responsive mitochondrial myopathy is a new phenotype of dihydrolipoamide dehydrogenase deficiency. The chaperon-like effect of vitamin B2.
Carrozzo R, Torraco A, Fiermonte G, Martinelli D, Di Nottia M, Rizza T, Vozza A, Verrigni D, Diodato D, Parisi G, Maiorana A, Rizzo C, Pierri CL, Zucano S, Piemonte F, Bertini E, Dionisi-Vici C.


Control of Mitochondrial pH by Uncoupling Protein 4 in Astrocytes Promotes Neuronal Survival.
Perreten Lambert H, Zenger M, Azarias G, Chatton JY, Magistretti PJ, Lengacher S.


Cellular, molecular and functional characterisation of YAC transgenic mouse models of Friedreich ataxia.
Anjomani Virmouni S, Sandi C, Al-Mahdawi S, Pook MA.


A systematic assessment of mitochondrial function identified novel signatures for drug-induced mitochondrial disruption in cells.
Li N, Oquendo E, Capaldi RA, Robinson JP, He YD, Hamadeh HK, Afshari CA, Lightfoot-Dunn R, Narayanan PK.


Energy metabolism analysis reveals the mechanism of inhibition of breast cancer cell metastasis by PEG-modified graphene oxide nanosheets.
Zhou T, Zhang B, Wei P, Du Y, Zhou H, Yu M, Yan L, Zhang W, Nie G, Chen C, Tu Y, Wei T.


Proteomic analysis of the mitochondria from embryonic and postnatal rat brains reveals response to developmental changes in energy demands.
Villeneuve LM, Stauch KL, Fox HS.


The atypical cadherin fat directly regulates mitochondrial function and metabolic state.
Sing A, Tsatskis Y, Fabian L, Hester I, Rosenfeld R, Serricchio M, Yau N, Bietenhader M, Shanbhag R, Jurisicova A, Brill JA, McQuibban GA, McNeill H.


B33 Non-neural Mitochondrial Impairment In Huntington's Disease Patients And Minipigs Transgenic For The N-terminal Part Of Human Mutated Huntingtin



Mitochondrial dysfunction in some triple-negative breast cancer cell lines: role of mTOR pathway and therapeutic potential.
Pelicano H, Zhang W, Liu J, Hammoudi N, Dai J, Xu RH, Pusztai L, Huang P.


The p38 Pathway Regulates Oxidative Stress Tolerance by Phosphorylation of Mitochondrial Protein IscU.
Tian L, Chen J, Chen M, Gui C, Zhong CQ, Hong L, Xie C, Wu X, Yang L, Ahmad V, Han J.


Antiangiogenic actions of vascular endothelial growth factor-A165b, an inhibitory isoform of vascular endothelial growth factor-A, in human obesity.
Ngo DT, Farb MG, Kikuchi R, Karki S, Tiwari S, Bigornia SJ, Bates DO, LaValley MP, Hamburg NM, Vita JA, Hess DT, Walsh K, Gokce N.


Dichloroacetate enhances apoptotic cell death via oxidative damage and attenuates lactate production in metformin-treated breast cancer cells.
Haugrud AB, Zhuang Y, Coppock JD, Miskimins WK.


Early oxidative shifts in mouse skeletal muscle morphology with high-fat diet consumption do not lead to functional improvements.
Thomas MM, Trajcevski KE, Coleman SK, Jiang M, Di Michele J, O'Neill HM, Lally JS, Steinberg GR, Hawke TJ.


Combined Strategies for Maintaining Skeletal Muscle Mass and Function in Aging: Myostatin Inactivation and AICAR-Associated Oxidative Metabolism Induction.
Pauly M, Chabi B, Favier FB, Vanterpool F, Matecki S, Fouret G, Bonafos B, Vernus B, Feillet-Coudray C, Coudray C, Bonnieu A, Ramonatxo C.


Cardiac diastolic dysfunction in high-fat diet fed mice is associated with lipotoxicity without impairment of cardiac energetics in vivo.
Abdurrachim D, Ciapaite J, Wessels B, Nabben M, Luiken JJ, Nicolay K, Prompers JJ.


The mitochondrial-targeted antioxidant MitoQ ameliorates metabolic syndrome features in obesogenic diet-fed rats better than Apocynin or Allopurinol.
Feillet-Coudray C, Fouret G, Ebabe Elle R, Rieusset J, Bonafos B, Chabi B, Crouzier D, Zarkovic K, Zarkovic N, Ramos J, Badia E, Murphy MP, Cristol JP, Coudray C.


Nuclear and cytoplasmic p53 suppress cell invasion by inhibiting respiratory Complex-I activity via Bcl-2 family proteins.
Kim EM, Park JK, Hwang SG, Kim WJ, Liu ZG, Kang SW, Um HD.


Peroxisomal ubiquitin-protein ligases peroxin2 and peroxin10 have distinct but synergistic roles in matrix protein import and peroxin5 retrotranslocation in Arabidopsis.
Burkhart SE, Kao YT, Bartel B.


Proteomics in neurodegenerative diseases: Methods for obtaining a closer look at the neuronal proteome.
Plum S, Steinbach S, Abel L, Marcus K, Helling S, May C.


The mitochondrial complex v-associated large-conductance inner membrane current is regulated by cyclosporine and dexpramipexole.
Alavian KN, Dworetzky SI, Bonanni L, Zhang P, Sacchetti S, Li H, Signore AP, Smith PJ, Gribkoff VK, Jonas EA.


Bioenergetic differences between MCF-7 and T47D breast cancer cells and their regulation by estradiol and tamoxifen.
Radde BN, Ivanova MM, Mai HX, Salabei JK, Hill BG, Klinge CM.


Stathmin mediates hepatocyte resistance to death from oxidative stress by down regulating JNK.
Zhao E, Amir M, Lin Y, Czaja MJ.


Neuronal and astrocyte dysfunction diverges from embryonic fibroblasts in the Ndufs4fky/fky mouse.
Bird MJ, Wijeyeratne XW, Komen JC, Laskowski A, Ryan MT, Thorburn DR, Frazier AE.


Mitochondrial chaperone TRAP1 activates the mitochondrial UPR and extends healthspan in Drosophila.
Baqri RM, Pietron AV, Gokhale RH, Turner BA, Kaguni LS, Shingleton AW, Kunes S, Miller KE.


Hyperglycemia- and neuropathy-induced changes in mitochondria within sensory nerves.
Hamid HS, Mervak CM, Münch AE, Robell NJ, Hayes JM, Porzio MT, Singleton JR, Smith A, Feldman E, Lentz SI.


A truncating PET100 variant causing fatal infantile lactic acidosis and isolated cytochrome c oxidase deficiency.
Ol??hov?? M, Haack TB, Alston CL, Houghton JA, He L, Morris AA, Brown GK, McFarland R, Chrzanowska-Lightowlers ZM, Lightowlers RN, Prokisch H, Taylor RW.


Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart.
Ashmore T, Fernandez BO, Branco-Price C, West JA, Cowburn AS, Heather LC, Griffin JL, Johnson RS, Feelisch M, Murray AJ.


Disrupting mitochondrial-nuclear coevolution affects OXPHOS complex I integrity and impacts human health.
Gershoni M, Levin L, Ovadia O, Toiw Y, Shani N, Dadon S, Barzilai N, Bergman A, Atzmon G, Wainstein J, Tsur A, Nijtmans L, Glaser B, Mishmar D.


Analysis of pro-apoptotic protein trafficking to and from mitochondria.
Vega-Naredo I, Cunha-Oliveira T, Serafim TL, Sardao VA, Oliveira PJ.


Mitochondriome and cholangiocellular carcinoma.
Bahitham W, Liao X, Peng F, Bamforth F, Chan A, Mason A, Stone B, Stothard P, Sergi C.


Role of mesenchymal stem cells in osteosarcoma and metabolic reprogramming of tumor cells.
Bonuccelli G, Avnet S, Grisendi G, Salerno M, Granchi D, Dominici M, Kusuzaki K, Baldini N.


Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations.
Gammage PA, Rorbach J, Vincent AI, Rebar EJ, Minczuk M.


Utrophin A is essential in mediating the functional adaptations of mdx mouse muscle following chronic AMPK activation.
Al-Rewashdy H, Ljubicic V, Lin W, Renaud JM, Jasmin BJ.


Viability and stress protection of chronic lymphoid leukemia cells involves overactivation of mitochondrial phosphoSTAT3Ser727.
Capron C, Jondeau K, Casetti L, Jalbert V, Costa C, Verhoyen E, Mass?? JM, Coppo P, B??n?? MC, Bourdoncle P, Cramer-Bord?? E, Dusanter-Fourt I.


Oncogenic properties of a spermatogenic meiotic variant of fer kinase expressed in somatic cells.
Yaffe E, Hikri E, Elkis Y, Cohen O, Segal A, Makovski A, Varvak A, Shpungin S, Nir U.


The Mitochondrial Complex V Associated Large-Conductance Inner Membrane Current Is Regulated by Cyclosporine and Dexpramipexole
Alavian KN, Dworetzky SI, Bonanni L, Zhang P, Sacchetti S, Li H, Signore AP, Smith PJ, Gribkoff VK, Jonas EA.


Two Siblings with Homozygous Pathogenic Splice Site Variant in Mitochondrial Asparaginyl-tRNA Synthetase (NARS2).
Vanlander AV, Menten B, Smet J, De Meirleir L, Sante T, De Paepe B, Seneca S, Pearce SF, Powell CA, Vergult S, Michotte A, De Latter E, Vantomme L, Minczuk M, Van Coster R.


c-Jun NH2-terminal kinase-induced proteasomal degradation of c-FLIPL/S and Bcl2 sensitize prostate cancer cells to Fas- and mitochondria-mediated apoptosis by tetrandrine.
Chaudhary P, Vishwanatha JK.


Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis.
Ortiz F, Acu??a-Castroviejo D, Doerrier C, Dayoub JC, L??pez LC, Venegas C, Garc??a JA, L??pez A, Volt H, Luna-S??nchez M, Escames G.


Effects of acute lipid overload on skeletal muscle insulin resistance, metabolic flexibility, and mitochondrial performance.
Dube JJ, Coen PM, DiStefano G, Chacon AC, Helbling NL, Desimone M, Stafanovic-Racic M, Hames KC, Despines AA, Toledo FG, Goodpaster BH.


Targeting of mitochondrial reactive oxygen species production does not avert lipid-induced insulin resistance in muscle tissue from mice.
Paglialunga S, van Bree B, Bosma M, Valdecantos MP, Amengual-Cladera E, J??rgensen JA, van Beurden D, den Hartog GJ, Ouwens DM, Bried?? JJ, Schrauwen P, Hoeks J.


Protein phosphatase 2C-alpha knockdown reduces angiotensin II-mediated skeletal muscle wasting via restoration of mitochondrial recycling and function



Succinate Dehydrogenase (SDH)-deficient Renal Carcinoma: A Morphologically Distinct Entity: A Clinicopathologic Series of 36 Tumors From 27 Patients.
Gill AJ, Hes O, Papathomas T, Sedivcov?? M, Tan PH, Agaimy A, Andresen PA, Kedziora A, Clarkson A, Toon CW, Sioson L, Watson N, Chou A, Paik J, Clifton-Bligh RJ, Robinson BG, Benn DE, Hills K, Maclean F, Niemeijer ND, Vlatkovic L, Hartmann A, et al.


Aberrant Histone Acetylation Promotes Mitochondrial Respiratory Suppression In the Brain of Alcoholic Rats.
Jung ME, Metzger DB.


Loss of mitochondrial exo/endonuclease EXOG affects mitochondrial respiration and induces ROS mediated cardiomyocyte hypertrophy.
Tigchelaar W, Yu H, De Jong AM, van Gilst WH, van der Harst P, Westenbrink BD, de Boer RA, Sillje HH.


Increasing NAD Synthesis in Muscle via Nicotinamide Phosphoribosyltransferase is not Sufficient to Promote Oxidative Metabolism.
Frederick DW, Davis JG, D??vila A Jr, Agarwal B, Michan S, Puchowicz MA, Nakamaru-Ogiso E, Baur JA.


Stem cells, neural progenitors, and engineered stem cells.
Rao RR, Iyer S.


[PDF] A two-week treatment with 2, 4-dinitrophenol does not affect muscle substrate oxidation and glucose homeostasis in WT and db/db mice



[PDF] The mitochondrial protein mitoNEET: a study of its role in mitochondrial oxidative capacity, substrate metabolism, and lipid accumulation in skeletal muscle in



The mitochondrial protein mitoNEET: a study of its role in mitochondrial oxidative capacity, substrate metabolism, and lipid accumulation in skeletal muscle



Early Expression of Parkinson's Disease-Related Mitochondrial Abnormalities in PINK1 Knockout Rats.
Villeneuve LM, Purnell PR, Boska MD, Fox HS.


Drosophila melanogaster LRPPRC2 is involved in coordination of mitochondrial translation.
Baggio F, Bratic A, Mourier A, Kauppila TE, Tain LS, Kukat C, Habermann B, Partridge L, Larsson NG.


Estrogen-mediated regulation of mitochondrial gene expression.
Lopez Sanchez MI, Shearwood AM, Chia TS, Davies SM, Rackham O, Filipovska A.


Increased body fat mass and tissue lipotoxicity associated with ovariectomy or high-fat diet differentially affects bone and skeletal muscle metabolism in rats.
Tagliaferri C, Salles J, Landrier JF, Giraudet C, Patrac V, Lebecque P, Davicco MJ, Chanet A, Pouyet C, Dhaussy A, Huertas A, Boirie Y, Wittrant Y, Coxam V, Walrand S.


Parkin-independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain.
Kageyama Y, Hoshijima M, Seo K, Bedja D, Sysa-Shah P, Andrabi SA, Chen W, H??ke A, Dawsn VL, Dawson TM, Gabrielson K, Kass DA, Iijima M, Sesaki H.


Mitochondrial Integrity in a Neonatal Bovine Model of Right Ventricular Dysfunction.
Bruns DR, Brown RD, Stenmark KR, Buttrick PM, Walker LA.


[HTML] Mitochondria in peroxisome-deficient hepatocytes exhibit impaired respiration, depleted DNA, and PGC-1? independent proliferation



Three minutes of all-out intermittent exercise per week increases skeletal muscle oxidative capacity and improves cardiometabolic health.
Gillen JB, Percival ME, Skelly LE, Martin BJ, Tan RB, Tarnopolsky MA, Gibala MJ.


A mutation in the human CBP4 ortholog UQCC3 impairs complex III assembly, activity and cytochrome b stability.
Wanschers BF, Szklarczyk R, van den Brand MA, Jonckheere A, Suijskens J, Smeets R, Rodenburg RJ, Stephan K, Helland IB, Elkamil A, Rootwelt T, Ott M, van den Heuvel L, Nijtmans LG, Huynen MA.


The Complex I Subunit NDUFA10 Selectively Rescues Drosophila pink1 Mutants through a Mechanism Independent of Mitophagy.
Pogson JH, Ivatt RM, Sanchez-Martinez A, Tufi R, Wilson E, Mortiboys H, Whitworth AJ.


Granzyme B-induced mitochondrial ROS are required for apoptosis.
Jacquemin G, Margiotta D, Kasahara A, Bassoy EY, Walch M, Thiery J, Lieberman J, Martinvalet D.


(-)-Epicatechin improves mitochondrial-related protein levels and ameliorates oxidative stress in dystrophic ??-sarcoglycan null mouse striated muscle.
Ramirez-Sanchez I, De Los Santos S, Gonzalez-Basurto S, Canto P, Mendoza-Lorenzo P, Palma-Flores C, Ceballos-Reyes G, Villarreal F, Zentella-Dehesa A, Coral-Vazquez R.


Proteomic Analysis and Functional Characterization of Mouse Brain Mitochondria during Aging Reveals Alterations in Energy Metabolism.
Stauch KL, Purnell PR, Villeneuve LM, Fox HS.


Age-related mitochondrial DNA depletion and the impact on pancreatic Beta cell function.
Nile DL, Brown AE, Kumaheri MA, Blair HR, Heggie A, Miwa S, Cree LM, Payne B, Chinnery PF, Brown L, Gunn DA, Walker M.


MTO1-Deficient Mouse Model Mirrors the Human Phenotype Showing Complex I Defect and Cardiomyopathy.
Becker L, Kling E, Schiller E, Zeh R, Schrewe A, H??lter SM, Mossbrugger I, Calzada-Wack J, Strecker V, Wittig I, Dumitru I, Wenz T, Bender A, Aichler M, Janik D, Neff F, Walch A, Quintanilla-Fend L, Floss T, Bekeredjian R, Gailus-Durner V, Fuchs H, et al.


Mitochondria dysfunction in lung cancer-induced muscle wasting in C2C12 myotubes.
McLean JB, Moylan JS, Andrade FH.


Bioenergetic differences between MCF-7 and T47D breast cancer cells and their regulation by estradiol and tamoxifen.
Radde BN, Ivanova MM, Mai HX, Salabei JK, Hill BG, Klinge CM.


OXPHOS dysfunction regulates integrin-??1 modifications and enhances cell motility and migration.
Nunes JB, Peixoto J, Soares P, Maximo V, Carvalho S, Pinho S, Vieira A, Paredes J, Rego AC, Ferreira IL, Gomez-Lazaro M, Sobrinho-Simoes M, Singh KK, Lima J.


ISCA2 mutation causes infantile neurodegenerative mitochondrial disorder.
Al-Hassnan ZN, Al-Dosary M, Alfadhel M, Faqeih EA, Alsagob M, Kenana R, Almass R, Al-Harazi OS, Al-Hindi H, Malibari OI, Almutari FB, Tulbah S, Alhadeq F, Al-Sheddi T, Alamro R, AlAsmari A, Almuntashri M, Alshaalan H, Al-Mohanna FA, Colak D, Kaya N.


Mitochondrial remodeling in mice with cardiomyocyte-specific lipid overload.
Elezaby A, Sverdlov AL, Tu VH, Soni K, Luptak I, Qin F, Liesa M, Shirihai OS, Rimer J, Schaffer JE, Wilson S C, Edward J M.


[PDF] An MRPS12 mutation modifies aminoglycoside sensitivity caused by 12S rRNA mutations



Permeabilization of brain tissue in situ enables multi-region analysis of mitochondrial function in a single mouse brain.
Herbst EA, Holloway GP.


Hypermethylation of cox5a promoter is associated with mitochondrial dysfunction in skeletal muscle of high fat diet-induced insulin resistant rats.
Gong YY, Liu YY, Li J, Su L, Yu S, Zhu XN, Cao XP, Xiao HP.


Fiber-type-specific sensitivities and phenotypic adaptations to dietary fat overload differentially impact fast- versus slow-twitch muscle contractile function in C57BL/6J mice.
Ciapaite J, van den Berg SA, Houten SM, Nicolay K, Willems van Dijk K, Jeneson JA.


[HTML] Development of mitochondrial targeting plasmid DNA nanoparticles: characterization and in vitro studies



Effect of p53 on mitochondrial morphology, import and assembly in skeletal muscle.
Saleem A, Iqbal S, Zhang Y, Hood DA.


Resistance Exercise Training Alters Mitochondrial Function in Human Skeletal Muscle.
Porter C, Reidy PT, Bhattarai N, Sidossis LS, Rasmussen BB.


Cofactor Strap regulates oxidative phosphorylation and mitochondrial p53 activity through ATP synthase.
Maniam S, Coutts AS, Stratford MR, McGouran J, Kessler B, La Thangue NB.


Genetic mosaic analysis of a deleterious mitochondrial DNA mutation in Drosophila reveals novel aspects of mitochondrial regulation and function.
Chen Z, Qi Y, French S, Zhang G, Garcia RC, Balaban R, Xu H.