Proteins > Bcl2 antagonist of cell death (Bad)
Bcl2 antagonist of cell death (Bad)
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UniProt Number:
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Q92934
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Alternate Names:
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Bcl-2-binding component 6, Bcl-2-like protein 8, Bcl-XL/Bcl-2-associated death promoter
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Structure and Function:
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Bad promotes cell death. Bad successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Bad can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 By similarity. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
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Disease Associations:
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n/a
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Protein Quantity Assays
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