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Enzymes > Adenine Nucleotide Translocase (ANT)
Adenine Nucleotide Translocase (ANT)
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UniProt Number:
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P12235
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Alternate Names:
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Adenine nucleotide translocator, ANT, Adenine nucleotide translocase, ADP/ATP carrier protein 1, Solute carrier family 25 member 1, ADP/ATP carrier protein, heart/skeletal muscle isoform T1
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Structure and Function:
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ANT is a reversible transporter of ATP and ADP. During OXPHOS the protein exchanges ATP out for ADP in, but when it becomes important to maintain a membrane potential, at times when OXPHOS is not working, ANT can work in reverse.
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Disease Associations:
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Mutant ANT has been identified in cardiomyopathy, and autoimmune reactions to this protein can cause heart related diseases.
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Monoclonal Antibodies
Immunocapture Kits
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