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Aldo-keto reductase family 1 member C1 (AKR1C1))


UniProt Number: Q04828
Alternate Names: 20-alpha-hydroxysteroid dehydrogenase, Chlordecone reductase homolog HAKRC
Structure and Function: Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation.
Disease Associations:


Monoclonal Antibodies
Cat. No. Name Reactivity Apps. Amount
ab131375 AKR1C1 antibody [4B6AF3] Human, Mouse, Rat WB, ICC/IF 100 µg



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